Methicillin-resistant staphylococcal colonization in dogs entering a veterinary teaching hospital

Hanselman, Beth; Kruth, Stephen A.; Weese, J. Scott

doi:10.1016/j.vetmic.2007.06.015

Cited by 101 publications

(122 citation statements)

References 20 publications

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“…Former studies revealed the prevalence rates of MRSP in dogs approximately between 0%-7% [21][22][23][24] . Unfortunately, there are several recent reports of MRSP isolates that exhibited high rates of prevalence in FarEastern parts of the world.…”

Section: Discussionmentioning

confidence: 99%

Methicillin Resistance in Staphylococcus pseudintermedius Isolated from Shelter Dogs in Turkey

Sareyyüpoğlu¹,

Müştak²,

Cantekin³

et al. 2014

Kafkas Univ Vet Fak Derg

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SummaryStaphylococcus pseudintermedius is a recently described species of staphylococci that is frequently isolated from dogs. The increase in antimicrobial resistance in staphylococci and transfer of S. pseudintermedius from infected pets to humans threaten the public health worldwide. In this study, it was aimed to determine the prevalence of S. pseudintermedius from skin infections of dogs and to determine the prevalence of methicillin-resistance in S. pseudintermedius isolates by phenotypic and genotypic methods. A total of 41 staphylococci were isolated from 53 dogs. Thirty three (80.4%) staphylococci were identified as S. pseudintermedius by PCR-RFLP analysis of pta gene. Methicillin resistance was also identified in 11 (33.3%) of these isolates by inoculation on chromogenic chromID MRSA agar, oxacillin disc diffusion method and the determination of mecA gene by PCR. This is the sole report in Turkey that described the situation of methicillin resistant S. pseudintermedius. Keywords: Dog, Staphylococcus pseudintermedius, Methicillin resistance Türkiye'deki Barınak Köpeklerinden İzole Edilen Staphylococcus pseudintermedius'larda Metisilin Direnci ÖzetStaphylococcus pseudintermedius, stafilokoklar içerisinde yeni tanımlanmış bir tür olup köpeklerden sıklıkla izole edilmektedir. Stafilokoklarda artan antimikrobiyal direnç ve S. pseudintermedius'un enfekte petlerden insanlara geçmesi, halk sağlığını tehdit etmektedir. Bu çalışmada, köpek deri enfeksiyonlarından izole edilen S. pseudintermedius'ların ve metisilin direncinin prevalansının fenotipik ve genotipik metotlar ile belirlenmesi amaçlanmıştır. Toplam 53 köpekten 41 stafilokok izole edildi. Stafilokok izolatlarının 33'ü (%80.4) pta geninin PCR-RFLP ile analiziyle S. pseudintermedius olarak belirlendi. Metisilin direnci kromogenik chromID MRSA agar, oxacillin disk difüzyon metodu ve mecA geninin belirlendiği PCR yöntemi ile bu izolatların 11'inde (%33.3) tespit edildi. Bu çalışma, Türkiye'de metisilin dirençli S. pseudintermedius'ların durumunu gösteren ilk bilimsel rapordur.

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Section: Discussionmentioning

confidence: 99%

Methicillin Resistance in Staphylococcus pseudintermedius Isolated from Shelter Dogs in Turkey

Sareyyüpoğlu¹,

Müştak²,

Cantekin³

et al. 2014

Kafkas Univ Vet Fak Derg

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“…Healthy animals can be colonized for variable periods of time without developing clinical disease [78], but the overall prevalence of the colonization remains low in dogs and cats [1,57,[79][80][81][82][83]. Potential differences with the human epidemiology of the disease, particularly the dynamics of colonization in companion animals (e.g.…”

Section: Occurrence In Companion Animalsmentioning

confidence: 99%

Reflection paper on MRSA in food-producing and companion animals: epidemiology and control options for human and animal health

et al. 2010

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SUMMARYThe scope of this reflection paper was to review the latest research on the risk of MRSA infection and colonization in animals. Attention focused on occurrence, risk factors for colonization and infection, and human contact hazard for livestock, horses, and companion animals. Whereas the clonal relationship between MRSA strains of CC398 is straightforward in livestock this is less obvious in horses. Small companion animals typically share MRSA strains that seem to exchange with a human reservoir. Management and therapeutic options have been suggested for livestock, horses, companion animals, as well as instructions on safety measures for persons in contact with animals. Conclusions were drawn with emphasis on future research activities, especially to confirm the apparent evolution of the organism and to demonstrate efficiency of control strategies.

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“…In the past, these strains were reported to be susceptible to beta-lactam antibiotics, but methicillin-resistant SIG, particulary S. pseudintermedius (MRSP) strains are being reported with increasing frequency (Gortel et al 1999, Vengust et al 2006, Zubeir et al 2007, van Duijkeren et al 2008. Methicillin-resistant S. pseudintermedius have been isolated from dogs, cats and humans (Hanselman et al 2007, Sasaki et al 2007, Wettstein et al 2008. As in MRSA, the methicillin resistance of S. pseudintermedius is mediated by the mecA gene.…”

Section: Introductionmentioning

confidence: 99%

Antibiotic resistance of canine Staphylococcus intermedius group (SIG) - practical implications

Chrobak¹,

Kizerwetter-Świda²,

Rzewuska³

et al. 2011

Polish Journal of Veterinary Sciences

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A total of 221 SIG strains were isolated from clinical samples of canine origin submitted to the Diagnostic Laboratory of the Division of Bacteriology and Molecular Biology at the Warsaw University of Life Sciences in Warsaw during the period 2006-2010. The aim of the study was to investigate the frequency of prevalence of methicillin-resistant SIG strains and to determine the MIC values of cephalotin, amoxicillin/clavulanic acid, ciprofloxacin, clindamycin, gentamicin, chloramphenicol, mupirocin for a collection of randomly selected 79 strains belonging to Staphylococcus intermedius group (SIG), including 23 mecA-positive and 56 mecA-negative strains. All isolates were identified as belonging to SIG based on their phenotypic properties and PCR amplification of S. intermedius-specific fragment of the 16S rRNA gene. The mecA gene was detected in 26 (12%) of 221 SIG strains. All tested mecA-negative SIG strains were susceptible to amoxicillin/clavulanic acid and cephalotin. One of the 56 mecA-negative SIG strains was resistant to ciprofloxacin, six (11%) to gentamicin. It was found that sixteen (29%) of 56 mecA-negative SIG strains were resistant to clindamycin. Most of the mecA-positive SIG strains were resistant to ciprofloxacin (96%), clindamycin (96%), and gentamicin (96%). Only one MRSIG strain was resistant to chloramphenicol. All examined mecA-positive SIG strains were found to be susceptible to mupirocin. Our results imply that staphylococcal multidrug resistance has become more prevalent, which could lead to difficulties in effective treatment. With some resistant strains the only therapeutic possibility are antimicrobial agents important in human medicine. New regulations for veterinary medicine concerning appropriate therapy of infections caused by multidrug-resistat staphylococci are needed.

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Methicillin-resistant staphylococcal colonization in dogs entering a veterinary teaching hospital

Cited by 101 publications

References 20 publications

Methicillin Resistance in Staphylococcus pseudintermedius Isolated from Shelter Dogs in Turkey

Methicillin Resistance in Staphylococcus pseudintermedius Isolated from Shelter Dogs in Turkey

Reflection paper on MRSA in food-producing and companion animals: epidemiology and control options for human and animal health

Antibiotic resistance of canine Staphylococcus intermedius group (SIG) - practical implications

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