Methicillin-resistant Staphylococcus aureus in hospitals in Tbilisi, the Republic of Georgia, are variants of the Brazilian clone

Bartels, Mette Damkjær; Nanuashvili, A.; Boye, Kasper; Rohde, Susanne Mie; Jashiashvili, N.; Faria, Natália; Kereselidze, Manana; Kharebava, S.; Westh, Henrik

doi:10.1007/s10096-008-0500-z

Cited by 21 publications

(13 citation statements)

References 14 publications

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“…Out of the remaining articles, 253 fulfilled our inclusion criteria (Shopsin et al, 1999; Graille et al, 2000; Fey et al, 2003; Arakere et al, 2005; Denis et al, 2005; Ko et al, 2005; Aires-de-Sousa et al, 2006, 2008; Deplano et al, 2006; Durand et al, 2006; Ferry et al, 2006, 2010; Fossum and Bukholm, 2006; Jury et al, 2006; Kuhn et al, 2006; Mellmann et al, 2006, 2008; Montesinos et al, 2006; Ruppitsch et al, 2006, 2007; Sabat et al, 2006; Cai et al, 2007, 2009; Conceicao et al, 2007; Cookson et al, 2007; Ellington et al, 2007a,b; Ghebremedhin et al, 2007; Hallin et al, 2007, 2008; Krasuski et al, 2007; Matussek et al, 2007; Otter et al, 2007; Tristan et al, 2007; Van Loo et al, 2007; Vourli et al, 2007; Werbick et al, 2007; Witte et al, 2007; von Eiff et al, 2007; Bartels et al, 2008, 2013, 2014; Chaberny et al, 2008; Chmelnitsky et al, 2008; Gardella et al, 2008; Fenner et al, 2008a,b; Golding et al, 2008, 2011; Ho et al, 2008a,b, 2012, 2016, 2017; Jappe et al, 2008; Karynski et al, 2008; Larsen et al, 2008, 2009; Nulens et al, 2008; Pérez-Vázquez et al, 2008; Strommenger et al, 2008; Vainio et al, 2008, 2011; Zhang et al, 2008, 2009; Alp et al, 2009; Argudín et al, 2009, 2011; Atkinson et al, 2009; Bekkhoucha et al, 2009; Chen et al, 2009; Chen H.-J. et al, 2010; Chen L. et al, 2010; Chen et al, 20...…”

Section: Resultsmentioning

confidence: 99%

Distribution of the Most Prevalent Spa Types among Clinical Isolates of Methicillin-Resistant and -Susceptible Staphylococcus aureus around the World: A Review

et al. 2018

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Background: Staphylococcus aureus, a leading cause of community-acquired and nosocomial infections, remains a major health problem worldwide. Molecular typing methods, such as spa typing, are vital for the control and, when typing can be made more timely, prevention of S. aureus spread around healthcare settings. The current study aims to review the literature to report the most common clinical spa types around the world, which is important for epidemiological surveys and nosocomial infection control policies.Methods: A search via PubMed, Google Scholar, Web of Science, Embase, the Cochrane library, and Scopus was conducted for original articles reporting the most prevalent spa types among S. aureus isolates. The search terms were “Staphylococcus aureus, spa typing.”Results: The most prevalent spa types were t032, t008 and t002 in Europe; t037 and t002 in Asia; t008, t002, and t242 in America; t037, t084, and t064 in Africa; and t020 in Australia. In Europe, all the isolates related to spa type t032 were MRSA. In addition, spa type t037 in Africa and t037and t437 in Australia also consisted exclusively of MRSA isolates. Given the fact that more than 95% of the papers we studied originated in the past decade there was no option to study the dynamics of regional clone emergence.Conclusion: This review documents the presence of the most prevalent spa types in countries, continents and worldwide and shows big local differences in clonal distribution.

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Section: Resultsmentioning

confidence: 99%

Distribution of the Most Prevalent Spa Types among Clinical Isolates of Methicillin-Resistant and -Susceptible Staphylococcus aureus around the World: A Review

et al. 2018

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“…Therefore, it was described as highly transmissible MRSA [59,60]. ST239 HA-MRSA is a growing MRSA group, which includes at least nine members (EMRSA-1, EM-RSA-4, EMRSA-7, EMRSA-11, and the Brazilian, Portuguese, Hungarian, Viennese, and Russian clones), and is widely spreading in Asia, South America, and Eastern Europe [44,[61][62][63][64][65][66].…”

Section: Ha-mrsamentioning

confidence: 99%

Community-acquired methicillin-resistant Staphylococcus aureus: community transmission, pathogenesis, and drug resistance

Yamamoto

Nishiyama

Takano

et al. 2010

Journal of Infection and Chemotherapy

135

167

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Methicillin-resistant Staphylococcus aureus (MRSA) is able to persist not only in hospitals (with a high level of antimicrobial agent use) but also in the community (with a low level of antimicrobial agent use). The former is called hospital-acquired MRSA (HA-MRSA) and the latter community-acquired MRSA (CA-MRSA). It is believed MRSA clones are generated from S. aureus through insertion of the staphylococcal cassette chromosome mec (SCCmec), and outbreaks occur as they spread. Several worldwide and regional clones have been identified, and their epidemiological, clinical, and genetic characteristics have been described. CA-MRSA is likely able to survive in the community because of suitable SCCmec types (type IV or V), a clone-specific colonization/infection nature, toxin profiles (including Pantone-Valentine leucocidin, PVL), and narrow drug resistance patterns. CA-MRSA infections are generally seen in healthy children or young athletes, with unexpected cases of diseases, and also in elderly inpatients, occasionally surprising clinicians used to HA-MRSA infections. CA-MRSA spreads within families and close-contact groups or even through public transport, demonstrating transmission cores. Re-infection (including multifocal infection) frequently occurs, if the cores are not sought out and properly eradicated. Recently, attention has been given to CA-MRSA (USA300), which originated in the US, and is growing as HA-MRSA and also as a worldwide clone. CA-MRSA infection in influenza season has increasingly been noted as well. MRSA is also found in farm and companion animals, and has occasionally transferred to humans. As such, the epidemiological, clinical, and genetic behavior of CA-MRSA, a growing threat, is focused on in this study.

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“…Multilocus sequence typing (MLST) identified TW20 as sequence type 239 (ST239), an international health care-associated (HA) MRSA lineage prevalent in Asia (19,38), South America (2, 37), and Eastern Europe (5,33), which includes EMRSA-1, -4, -7, and -11 and the Brazilian, Portuguese, Hungarian, and Viennese clones (24). To investigate the genetic basis for increased resistance and transmissibility, the TW20 genome was completely sequenced, assembled, and finished and annotated as described previously (16,25).…”

mentioning

confidence: 99%

Genome Sequence of a Recently Emerged, Highly Transmissible, Multi-Antibiotic- and Antiseptic-Resistant Variant of Methicillin-Resistant Staphylococcus aureus , Sequence Type 239 (TW)

et al. 2010

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Methicillin-resistant Staphylococcus aureus in hospitals in Tbilisi, the Republic of Georgia, are variants of the Brazilian clone

Cited by 21 publications

References 14 publications

Distribution of the Most Prevalent Spa Types among Clinical Isolates of Methicillin-Resistant and -Susceptible Staphylococcus aureus around the World: A Review

Distribution of the Most Prevalent Spa Types among Clinical Isolates of Methicillin-Resistant and -Susceptible Staphylococcus aureus around the World: A Review

Community-acquired methicillin-resistant Staphylococcus aureus: community transmission, pathogenesis, and drug resistance

Genome Sequence of a Recently Emerged, Highly Transmissible, Multi-Antibiotic- and Antiseptic-Resistant Variant of Methicillin-Resistant Staphylococcus aureus , Sequence Type 239 (TW)

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