Méthodes non invasives de mesure de la densité minérale osseuse

Roux, Christian

doi:10.1051/medsci/2003192231

Cited by 1 publication

(2 citation statements)

References 33 publications

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“…Theneed for great precision is justified by the relationship between reproducibility andsensitivity (34).The smallest individual detectable differencei nB MD is 2 √ 2.CV (36). This meanst hate venw henc onsidering the best reproducibilityo ft his study (CV =2.91%), the lowest individual signifi-cantBMD variation whichcan be attributed to ab iological phenomenon, andn ot to a technicalv ariation,i sn ot lesst han8 .23%.…”

Section: Discussionmentioning

confidence: 95%

“…Because of expensea nd apparatus design, QCTi sr estrictedt o ex-vivo or ex situ experimental fields in the horse (9,37). Dual-energy X-raya bsorptiometry( DXA) expresses BMD pers urface unit (g/cm 2 )i gnoring bone depth in contrast with QCT.S ingleenergy X-raya bsorptiometry( SXA)a nd morer ecentlyD XA, are the mostw idely used systemsf or osteoporosis diagnosis (23,35,36). Largea pparatus allowing whole human body scanning andearly vertebral fracture risk detection (18), areo nly usable for ex-vivo experimentalapplications in the horse ( 8,14,15,29).…”

Section: Introductionmentioning

confidence: 99%

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Third metacarpal bone mineral density assessment in the standing horse by dual X-ray absorptiometry

Delguste¹,

Perona²,

Lebecque³

et al. 2005

Vet Comp Orthop Traumatol

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Bone mineral density (BMD) is correlated to mechanical properties of bone. In the horse, dual energy X-ray absorptiometry (DXA) has yet only been performed ex-vivo, but a new portable DXA device would be ideal for in-vivo BMD measurement. We explored field suitability, precision and accuracy of this device for in-vivo third metacarpal density assessment. Precision was analysed by calculating measurement variation under repeated measurement tests with (reproducibility) and without (repeatability) limb repositioning. Repeatability and reproducibility were tested ex-vivo, at the same time that intra- and inter-operator reproducibility were assessed in-vivo. In order to test accuracy, bone mineral content (BMC) of several bone samples determined by DXA and ashing were compared. Repeatability was 1.47% and reproducibility 1.69% ex-vivo. In-vivo reproducibility varied between 2.91 and 4.06% for intra-operator test and between 3.13 and 5.53% for inter-operator test. BMC measured by DXA and ash weight were highly correlated (R2>0.99). In conclusion, under described conditions this DXA device is usable, accurate and precise. Its sensitiveness reaches 8.23% in an individual longitudinal monitoring. Using the third metacarpal bone as an example, we have shown that this device is suitable for experimental or clinical monitoring.

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Section: Discussionmentioning

confidence: 95%