The article is devoted to the identification and analysis of cross-program effects in the sphere of small and medium-sized businesses that are formed during the implementation of state programs of the Kurgan region. The relevance and usefulness of identifying inter-program connections are proved. The state programs of the Kurgan region that form the effects in the sphere of small and medium-sized businesses in the region are identified. Groups of cross-program effects were formed and the number of state programs and their activities that form various types of effects in the sphere of small and medium-sized businesses in the region was found. The assessment of cross-program effects for each task of the program of small and medium-sized businesses development in the region was carried out. The paper presents quantitative results of assessment of cross-program effects value created by state programs for each group of cross-program effects and each task of the program for the development of small and medium-sized businesses in the region.