This paper focuses on the aerodynamic and structural design of the cascade within a cold stream thrust reverser. Methodologies are established for improving the efficiency of the design process. Aerodynamic and structural simulations are carried out using realistic operating conditions for idealized cascade models representing three design options. The aim of this work is to minimize weight while maintaining or improving aerodynamic and structural performance. Total reverse thrust decreases by 0.28 per cent when the aerodynamic performance of the deformed cascade is compared with the undeformed case. This shows that, for the conditions tested, the displacement of the cascade vanes has a minimal affect on aerodynamic performance, and that there is scope for weight reduction. When cascade weight is reduced by 5 per cent and then 10 per cent by modifying the vane configurations, the structural performance of the cascade improves, with significantly reduced levels of vane displacement. Although reverse thrust is reduced by 9 per cent for both of the reduced-weight designs, the maximum airspeed within the thrust reverser is subsonic. The maximum airspeed is above Mach 1 for the original design. This reduces the risk of the structure being subjected to the complex loading conditions associated with the shock waves due to supersonic air flow.