2001
DOI: 10.1002/jmri.1073
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Methodology of brain perfusion imaging

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Cited by 376 publications
(303 citation statements)
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References 241 publications
(350 reference statements)
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“…The correction term (z) in Equation (1) corrects for insufficient relaxation, since labeled and unlabeled images were acquired in an interleaved manner, and since the spin-labeling time was much less than 3 times T 1 * (Barbier et al, 2001); z ¼ ð1 À e ÀT lab =T Ã 1 Þ, where T lab is the time span for the spin-preparation period (2.4 secs); and T 1 * is the apparent T 1 value of tissue without MT but including CBF contributions, which is B1.9 secs (Kim and Kim, 2002).…”
Section: Data Processingmentioning
confidence: 99%
“…The correction term (z) in Equation (1) corrects for insufficient relaxation, since labeled and unlabeled images were acquired in an interleaved manner, and since the spin-labeling time was much less than 3 times T 1 * (Barbier et al, 2001); z ¼ ð1 À e ÀT lab =T Ã 1 Þ, where T lab is the time span for the spin-preparation period (2.4 secs); and T 1 * is the apparent T 1 value of tissue without MT but including CBF contributions, which is B1.9 secs (Kim and Kim, 2002).…”
Section: Data Processingmentioning
confidence: 99%
“…The measured MR signal s m in a vessel is then s m ϭ ks a ϩ ͑1 Ϫ k͒s t , [ 1 ] where k denotes the volume fraction of blood in the voxel(s). In the limit ͑1 Ϫ k͒s t much smaller than s a , [ 2 ] where the tissue contribution is much smaller than the arterial contribution,…”
Section: Pve and Aif Rescalingmentioning
confidence: 99%
“…Magnetic resonance perfusion imaging based on bolustracking is widely used to measure cerebral blood flow (CBF) (1,2). Absolute quantification of CBF requires accurate determination of the arterial input function (AIF) (2)(3)(4)(5), defined as the concentration of contrast agent that enters the brain tissue as a function of time.…”
mentioning
confidence: 99%
“…Generally speaking, two different ASL strategies have been developed: pulsed ASL (PASL), in which a thick, but well defined, slab of blood is inverted prior to entering the volume of interest in the brain; or continuous ASL (CASL), in which arterial blood flowing proximal to the COW is continuously inverted prior to entering the volume of interest in the brain. Comprehensive reviews have been written on the technical details of implementation and applications of ASL (32)(33)(34)(35), to which the reader is referred for further reference.…”
Section: General Principles Of Mapping Vascular Territories With Aslmentioning
confidence: 99%