In milling contour profiles, tools create minute surface variations known as roughness. An algorithm is proposed to analyze the profile dimensional variation in milled parts by an artificial vision and Fourier descriptors as a measurement technique. The proposed method is based on the Fourier spectrum to analyze three profile signatures extracted from an image of a milled part with the aim of measuring the variation in three materials. It is found that when performing the profile machining process, the combination of the parameters: spindle speed, feed rate, cutting depth, and coolant fluid influence the dimensional variation of the part. The proposed approach concludes that this inspection method is faster and more efficient to guarantee the quality of parts manufactured by machining.