In order to improve the operating stability of the mine hoisting system and provide reference and guidance for monitoring the mining shaft deformation (MSD), the operating characteristics of the hoisting conveyance (OCHC) under MSD are studied. Firstly, a simplified finite element model based on spring element is established for analyzing the guide rail (GR) deformation law under MSD, and the deformation result calculated by ANSYS is transformed into the geometric model in the dynamics model. Secondly, the transversal-longitudinal coupling relationship of the guide roller (GRO) is analyzed, and it is deduced that the variation law of the contact relationship between the guide roller and rail (GROR) with its deformation and the HC position. On the basis of the above, the dynamics model of the mine hoisting system established by ADAMS is verified by experiment and used to analyze the operating characteristics (OC) under different types and degrees and connection states. The analysis results show that the deformation result transformation of GR can characterize the SD trend and the connection state between the bunton and shaft and GR under MSD and can realize the co-simulation of ANSYS and ADAMS, which makes the dynamic model can accurately reflect the OCHC under MSD. The displacement and vibration acceleration of HC in MSD direction, angular displacement (AD) around its vertical axis and buffer relative displacement (BRD) are highly sensitive to the deformation and contain prominent feature, which can realize the characterization of the deformation. The vibration acceleration of hoisting conveyance (VAHC) and the BRD in the deformation direction produce a prominent impact response to the disconnection between the bunton and guide rail (BGR). The disconnection of the bunton from shaft only changes the frequency and amplitude of the low-frequency oscillation of BRD near disconnection position. It can provide a basis for identifying MSD and mitigating its effect on HC.