Methods of Extraction: Maceration, Percolation and Decoction

Hidayat, Rachmat; Wulandari, Patricia

doi:10.37275/ehi.v2i1.15

Cited by 20 publications

(10 citation statements)

References 19 publications

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“…This extraction method was preferred based on the unknown nature, labile or thermolabile, of the compounds in the mixture. Furthermore, this method has been used to extract various phytoconstituents, including phenolics (Hidayat and Wulandari, 2021). The qualitative phytochemical analysis of the recipe showed the presence of various secondary metabolites such as tannins, saponins, flavonoids, sterols, triterpenes, and coumarins.…”

Section: Discussionmentioning

confidence: 99%

Polyphenol content, antioxidant and antiproliferative effects of a plant mixture composed of four medicinal plants with hepatoprotective potential

Boly,

Kindo,

Traore

et al. 2023

Afr. J. Pharm. Pharmacol.

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Reactive oxygen species (ROS), known as normal by-products of various cellular processes, are involved in several human diseases, including cancer and liver diseases. The present study aimed to (i) determine the polyphenol contents, (ii) assess the antioxidant, and (iii) antiproliferative effects of a mixture composed of Balanites aegyptiaca, Calotropis procera, Cochlospermum tinctorium, and Acanthospermum hispidum. These plants are reported to elicit various properties, including antioxidant, hepatoprotective, and anticancer. The phytochemicals were screened qualitatively, and Folin and Ciocalteu as well as aluminium chloride were used as reagents, to measure the total phenolics (TPC) and flavonoids (TFC), respectively. The antioxidant assay used four assays: DPPH, ABTS, FRAP, and LPO. The antiproliferative effect of the mixture was investigated on the human hepatocarcinoma cell line Hep3B. The phytochemical screening revealed the presence of saponins, flavonoids, tannins, sterols, coumarins, and triterpenes. The mixture seems richer in total phenolics (208.81 ± 1.13 mg GAE/g extract) than flavonoids (10.74 ± 1.44 mg QE/g extract). Regarding the radical scavenging activity, the mixture significantly inhibited ABTS radicals with an IC 50 value of 11.61 ± 0.0006 µg/ml. Moreover, it was potent in reducing ferric iron (133.06 mol AAE/g) and inhibiting lipid peroxidation (inhibition percentage equal to 56.39%). The mixture showed a considerable antiproliferative effect against the Hep3B cells with an IC50 value of 1.1 ± 0.75 µg/mL The beneficial effects attributed to the mixture may be explained by the presence of phenolics known for their potent antioxidant properties. The study findings suggest a promising synergistic plant combination for protecting the liver from oxidative stress and cancer. However, more detailed studies are needed to identify and confirm the antioxidant and antiproliferative mechanisms of action.

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Section: Discussionmentioning

confidence: 99%

Polyphenol content, antioxidant and antiproliferative effects of a plant mixture composed of four medicinal plants with hepatoprotective potential

Boly,

Kindo,

Traore

et al. 2023

Afr. J. Pharm. Pharmacol.

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“…In this method, the sample is soaked in a solvent/menstruum (aqueous and non-aqueous) such as water, ethanol, methanol, petroleum ether, etc. ( Figure 1 ), for 3–7 days with occasional shaking to extract the phytochemicals [ 135 ]. After maceration, the liquid is strained out, and the solid residue (Marc) is pressed to extract as much liquid as possible.…”

Section: Phytochemical Extraction Methodsmentioning

confidence: 99%

“…The high temperature used in the decoction process inhibits the action of glucuronidase, preventing glycosides from being converted to their aglycones. This leads to the detection of higher levels of flavones (Baicalin and Wogonin) in the extracted decoctions [ 135 ]. The major limitations of decoction are the high level of impurities present in the crude extract.…”

Section: Phytochemical Extraction Methodsmentioning

confidence: 99%

Major Phytochemicals: Recent Advances in Health Benefits and Extraction Method

et al. 2023

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Recent scientific studies have established a relationship between the consumption of phytochemicals such as carotenoids, polyphenols, isoprenoids, phytosterols, saponins, dietary fibers, polysaccharides, etc., with health benefits such as prevention of diabetes, obesity, cancer, cardiovascular diseases, etc. This has led to the popularization of phytochemicals. Nowadays, foods containing phytochemicals as a constituent (functional foods) and the concentrated form of phytochemicals (nutraceuticals) are used as a preventive measure or cure for many diseases. The health benefits of these phytochemicals depend on their purity and structural stability. The yield, purity, and structural stability of extracted phytochemicals depend on the matrix in which the phytochemical is present, the method of extraction, the solvent used, the temperature, and the time of extraction.

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“…Extraction involves separating the active parts of the plant as drugs using selectivity and standards [40]. Here are some stages of natural product extraction: (1) the solvent penetrates into the solid matrix; (2) the solute dissolves in the solvent; (3) the solute diffuses out of the solid matrix; (4) the extracted solute is collected [41]. [42] in his review explains that there are several factors to consider in the extraction process, including the nature of the solvent to be used, particle size of the raw material, solvent ratio, extraction temperature and duration.…”

Section: Sanrego (Lunasia Amara Blanco) Extractionmentioning

confidence: 99%

Bioactive Compounds of Sanrego (Lunasia AmaraBlanco.) Extracted Using Different Methods: A Review

Dhani Putri,

Bakar Tawali

2024

BIO Web Conf.

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The use of plants as medicine has been trusted by the community since time immemorial. Sanrego (Lunasia amara Blanco.) is one plant that has been believed to be an aphrodisiac. Sanrego is a wild plant found in the forests of Sulawesi, Java, Borneo, Maluku, Philippines, Papua New Guinea and Australia, and belongs to the Rutaceae Family. Sanrego has several properties such as treating stomach pain, anti-inflammatory, anti-cancer, snake bites and increasing sexual aggressiveness. This is because sanrego has bioactive ingredients as pharmacological. Sanrego extract contains secondary metabolites or bioactive compounds that include flavanoids, tannins, alakloids, steroids and saponins. Given the large variety of bioactive compounds in a sanrego plant, it is necessary to pay attention to extraction techniques in filtering these compounds. Some environmentally friendly extraction methods that can be used include maceration extraction methods, soxhlet, reflux, ultasonic, microwave, and enzyme assistance. This review discusses and describes the various extraction techniques used to obtain plant bioactive compounds. These extraction techniques include conventional extraction techniques and non-conventional extraction techniques. This review analyzes the advantages and disadvantages of this extraction technique. This review covers the application of extraction methods to sanrego plants.

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Methods of Extraction: Maceration, Percolation and Decoction

Cited by 20 publications

References 19 publications

Polyphenol content, antioxidant and antiproliferative effects of a plant mixture composed of four medicinal plants with hepatoprotective potential

Polyphenol content, antioxidant and antiproliferative effects of a plant mixture composed of four medicinal plants with hepatoprotective potential

Major Phytochemicals: Recent Advances in Health Benefits and Extraction Method

Bioactive Compounds of Sanrego (Lunasia AmaraBlanco.) Extracted Using Different Methods: A Review

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