Methods of literature review and synthesis

Coronado, Boris E.; Bu, Davis; Levey, Andrew S.; Meyer, Klemens B.

doi:10.1053/ajkd.1998.v32.pm9820464

Cited by 3 publications

(1 citation statement)

References 362 publications

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“…In such instances, it is recommended to follow the method developed by the National Kidney Foundation Taskforce on CVD in Chronic Renal Disease, which provides criteria for the extrapolation of evidence from RCTs on CVD interventions in the general population to populations with CKD. 19 The following questions help determine whether the evidence from the non-CKD population is applicable to a CKD population of interest and how directly it may apply when grading the directness of the evidence. a.…”

Section: Extrapolation Of Evidence From Non-ckd To Ckd Populationsmentioning

confidence: 99%

Grading evidence and recommendations for clinical practice guidelines in nephrology. A position statement from Kidney Disease: Improving Global Outcomes (KDIGO)

Uhlig

MacLeod

Craig

et al. 2006

Kidney International

181

107

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Considerable variation in grading systems used to rate the strength of guideline recommendations and the quality of the supporting evidence in Nephrology highlights the need for a uniform, internationally accepted, rigorous system. In 2004, Kidney Disease: Improving Global Outcomes (KDIGO) commissioned a methods expert group to recommend an approach for grading in future nephrology guidelines. This position statement by KDIGO recommends adopting the Grades of Recommendation Assessment, Development, and Evaluation (GRADE) approach for the grading of evidence and guidelines on interventions. The GRADE approach appraises systematic reviews of the benefits and harms of an intervention to determine its net health benefit. The system considers the design, quality, and quantity of studies as well as the consistency and directness of findings when grading the quality of evidence. The strength of the recommendation builds on the quality of the evidence and additional considerations including costs. Adaptations of the GRADE approach are presented to address some issues pertinent to the field of nephrology, including (1) the need to extrapolate from studies performed predominantly in patients without kidney disease, and (2) the need to use qualitative summaries of effects when it is not feasible to quantitatively summarize them. Further refinement of the system will be required for grading of evidence on questions other than those related to intervention effects, such as diagnostic accuracy and prognosis.

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Section: Extrapolation Of Evidence From Non-ckd To Ckd Populationsmentioning

confidence: 99%