Methotrexate-induced cutaneous ulceration and necrosis in chronic atopic dermatitis

Ladha, Malika A.; Edgerton, Bryn; Levy, Jonathan M.; Mahmood, Muhammad Nateque; Devani, Alim; Grewal, Parbeer; Prajapati, Vimal H.

doi:10.1016/j.jdcr.2020.02.028

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“… 2 More recently, MTX-induced ulcers have complicated treatment of other dermatologic conditions such as bullous pemphigoid, cutaneous T-cell lymphoma, and atopic dermatitis. 3 Ulcerations commonly present within involved skin and are accompanied by pancytopenia. 3 , 4 Morbidity from this medication toxicity can be high, and it has been associated with several deaths in patients with psoriasis and cutaneous T-cell lymphoma.…”

Section: Discussionmentioning

confidence: 99%

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Methotrexate-induced cutaneous ulceration without pancytopenia in a patient treated for inflammatory arthritis

Berna

DaSilva

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JAAD Case Reports

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Section: Discussionmentioning

confidence: 99%

“… 3 Ulcerations commonly present within involved skin and are accompanied by pancytopenia. 3 , 4 Morbidity from this medication toxicity can be high, and it has been associated with several deaths in patients with psoriasis and cutaneous T-cell lymphoma. 2 , 4 …”

Section: Discussionmentioning

confidence: 99%