Methyl farnesoate controls adult male morphogenesis in the crayfish, Procambarus clarkii

Laufer, Hans; Demir, Neslihan; Pan, Xuejun; Stuart, James D.; Ahl, Jonna

doi:10.1016/j.jinsphys.2005.02.007

Cited by 73 publications

(45 citation statements)

References 18 publications

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“…It was quite different with the previous findings that the ovary was mediated by external gonadotropic hormones, such as methyl farnesoate (MF), which synthesized by the mandibular organ (Laufer et al, 1998(Laufer et al, , 2005Reddy et al, 2004;Nagaraju, 2007;Miyakawa et al, 2014;Gong et al, 2016). And Methoprene-tolerant (Met) has been suggested to be a receptor of MF in crustaceans (Miyakawa et al, 2013(Miyakawa et al, , 2014Shyamal et al, 2015).…”

Section: Discussioncontrasting

confidence: 79%

A bone morphogenetic protein ligand and receptors in mud crab: A potential role in the ovarian development

Shu

Yang

Huang

et al. 2016

Molecular and Cellular Endocrinology

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Section: Discussioncontrasting

confidence: 79%

A bone morphogenetic protein ligand and receptors in mud crab: A potential role in the ovarian development

Shu

Yang

Huang

et al. 2016

Molecular and Cellular Endocrinology

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“…Associated but unusual compounds, such as JHs in insects and MF in crustaceans, exhibit similar functions (Gilbert et al 2000). MF is established as a major morphogen in crustaceans (Laufer et al 2005, Nagaraju & Borst 2008. MF is a key endocrine controller of crustacean molting, reproduction, osmoregulation, behavior, morphogenesis, and metabolism (see reviews Nagaraju (2007Nagaraju ( , 2011).…”

Section: Discussionmentioning

confidence: 99%

Molecular cloning and sequence of retinoid X receptor in the green crab Carcinus maenas: a possible role in female reproduction

Nagaraju

Rajitha

Borst³

2011

Journal of Endocrinology

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Retinoid X receptor (RXR) belongs to an ancient superfamily of nuclear hormone receptors, and plays an important role in reproduction of vertebrates. However, the reproductive role of RXR has not been clarified in crustaceans. In this investigation, we first report the cloning of two alternative splice variants of RXR cDNA from green crab ovarian RNA. RXR mRNA levels were quantified in different vitellogenic stages of the crab hepatopancreas (HP) and ovary. The expression of RXR mRNA relative to the arginine kinase mRNA was significantly increased in the HP of vitellogenic crabs in a stage-dependent manner. The relative levels of RXR mRNA in the ovary were significantly lower in vitellogenic stage III crabs than in crabs in the other three stages. These data indicate that the HP and ovary of the crab are capable of expressing RXR, which may regulate, in part, vitellogenesis in the crab. We also examined the effects of methyl farnesoate (MF) and RXR-dsRNA treatments on vitellogenin and RXR gene expression. Vitellogenin and RXR mRNA levels in HP and ovarian fragments incubated in MF were significantly (P!0 . 001) higher than in control tissue fragments prepared from the same animal. Treatment of crabs with RXR-dsRNA significantly (P!0 . 001) reduced mRNA levels for RXR and for vitellogenin as well as MF levels in hemolymph. These results indicate that, MF and RXR form a complex (MF-RXR) directly and together stimulate ovarian development in these green crabs. This interaction of RXR, MF, and ovary development axis is a novel finding and is the first report to the best of our knowledge.

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“…In M. rosenbergii the levels of MF rise during premolt stage and decline during postmolt stage [31] and also accelerates molt in P. clarkii [31] and crab O. senex senex [32]. Olmstead and Leblanc [33] found antagonist of JH as methoprene decreases molt frequency in D. magna.…”

Section: Role Of Methyl Farnesoate (Mf) On Moltingmentioning

confidence: 95%

Crustacean Molting: Regulation and Effects of Environmental Toxicants

Hosamani¹,

B²,

P³

2017

J Marine Sci Res Dev

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In crustaceans the growth of the animal occurs by shedding of old exoskeleton and formation of new exoskeleton. Immediately after ecdysis the newly synthesized cuticle up takes water to expand new exoskeleton thereby size. Molt cycle in crustaceans is under the control of several regulatory hormones, internal and external factors. The predominant hormones molt inhibiting hormone (MIH) and ecdysteroids act in a controversy manner to one another in regulation of molt. It is also identified that the methyl farnesoate (MF) induces molting by inducing the synthesis and release of ecdysteroids from Y-organs. Besides several other hormones and internal molecules like opioids and neurotransmitters along with toxicants (xenobiotics, chemicals and metals) are also involved in the regulation of crustacean molting. Toxicity of aquatic pollutants leads to retardation of growth and delays molting, besides influence mortality and causes huge loss to crustacean farming. This review presents the advances in the field of crustacean molting and its regulation.

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Methyl farnesoate controls adult male morphogenesis in the crayfish, Procambarus clarkii

Cited by 73 publications

References 18 publications

A bone morphogenetic protein ligand and receptors in mud crab: A potential role in the ovarian development

A bone morphogenetic protein ligand and receptors in mud crab: A potential role in the ovarian development

Molecular cloning and sequence of retinoid X receptor in the green crab Carcinus maenas: a possible role in female reproduction

Crustacean Molting: Regulation and Effects of Environmental Toxicants

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