Methylotrophic Cell Factory as a Feasible Route for Production of High-Value Chemicals from Methanol

Cui, Lanyu; Zhang, Chong; Xing, Xin‐Hui

doi:10.1007/978-3-319-74866-5_13

Cited by 2 publications

(1 citation statement)

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“…Due to the limited rigidity and brittleness of the PHB structure, further studies were focused on functionalized PHAs containing C–C double bonds produced when unsaturated carboxylic acids were used as an auxiliary carbon source [ 19 , 20 ]. The co-polyester poly-3-hydroxybutyrate-poly-3-hydroxyvalerate (PHB/HV) was accumulated in Methylobacterium sp.…”

Section: Introductionmentioning

confidence: 99%

Current advance in bioconversion of methanol to chemicals

Zhang

Song

Qiao

et al. 2018

Biotechnol Biofuels

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Methanol has become an attractive substrate for biotechnological applications due to its abundance and low-price. Chemicals production from methanol could alleviate the environmental concerns, costs, and foreign dependency associated with the use of petroleum feedstock. Recently, a growing fraction of research has focused on metabolites production using methanol as sole carbon and energy source or as co-substrate with carbohydrates by native or synthetic methylotrophs. In this review, we summarized the recent significant progress in native and synthetic methylotrophs and their application for methanol bioconversion into various products. Moreover, strategies for improvement of methanol metabolism and new perspectives on the generation of desired products from methanol were also discussed, which will benefit for the development of a methanol-based economy.

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Section: Introductionmentioning

confidence: 99%