2012
DOI: 10.3402/ejpt.v3i0.19392
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Methylphenidate does not restore the reduced serum BDNF levels in ADHD children

Abstract: Statement of the problem: Brain-derived neurotrophic factor (BDNF) is a member of the neurotrophin family of trophic factors, which is the most abundant neurotrophin in the brain. BDNF exerts its effects by binding to the tropomyosin-related kinase B (TrkB) receptor. It enhances the growth and maintenance of several neuronal systems, serves as a neurotransmitter modulator, and participates in mechanisms of neuronal plasticity, such as long-term potentiation and learning. We aim to quantify the basal concentrat… Show more

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