Metronomic chemotherapy in cancer treatment: new wine in an old bottle

Wu, Huai-liang; Zhou, Han-xing; Chen, Li-min; Wang, Shu-sen

doi:10.7150/thno.95619

Theranostics

2024

DOI: 10.7150/thno.95619

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Metronomic chemotherapy in cancer treatment: new wine in an old bottle

Huai-liang Wu,

Han-xing Zhou,

Li-min Chen

et al.

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References 177 publications

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Emerging strategies in cancer immunotherapy: Expanding horizons and future perspectives

Akunne,

Anulugwo,

Azu

2024

IJMIO

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Cancer immunotherapy has revolutionized oncology by harnessing the body’s immune system to target and eradicate malignant cells. This review delves into emerging strategies in cancer immunotherapy, focusing on novel approaches and future directions of this rapidly evolving field. Key areas of exploration include immune checkpoint inhibitors (ICIs), chimeric antigen receptor (CAR) T-cell therapy, and cancer vaccines. ICIs, which target proteins such as cytotoxic T-lymphocyte antigen-4 and programmed cell death-1/programmed cell death ligand 1, have shown significant efficacy in various cancers, transforming clinical outcomes. CAR-T cell therapy, with its ability to genetically modify T-cells to attack cancer cells, has demonstrated remarkable success in hematologic malignancies and is being adapted for solid tumors. Cancer vaccines designed to stimulate an immune response against specific tumor antigens are also advancing with promising clinical results. Despite these advances, challenges such as immunogenicity, side effects, and treatment resistance remain. This review provides a comprehensive overview of the latest developments, clinical trials, and future perspectives in cancer immunotherapy, highlighting the potential for these strategies to redefine cancer treatment.

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Emerging strategies in cancer immunotherapy: Expanding horizons and future perspectives

Akunne,

Anulugwo,

Azu

2024

IJMIO

View full text Add to dashboard Cite

show abstract

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Metronomic chemotherapy in cancer treatment: new wine in an old bottle

Cited by 1 publication

References 177 publications

Emerging strategies in cancer immunotherapy: Expanding horizons and future perspectives

Emerging strategies in cancer immunotherapy: Expanding horizons and future perspectives

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