METTL3 Promotes Proliferation and Myogenic Differentiation Through m ⁶A RNA Methylation/YTHDF1/2 Signaling Axis in Myoblasts

Editorial: Osteoporosis and the Role of Muscle

“…Knockdown of METTL 3 suppresses expression of runx2 and osterix, which are critical steps in osteoblastogenesis and can also reduce expression of VEGF. M 6 A in muscle myoblasts controls their transition to other muscle cell states (3,4). This is an epigenetic factor that exists in both bone and skeletal muscle and the coordination of actions in both tissues is worth further study.…”