The present study considers two-dimensional mathematical modeling of non-Newtonian nanofluid hemodynamics with heat and mass transfer in a stenosed coronary artery in the presence of a radial magnetic field. The second-grade differential viscoelastic constitutive model is adopted for blood to mimic non-Newtonian characteristics, and blood is considered to contain a homogenous suspension of nanoparticles. The Vogel model is employed to simulate the variation of blood viscosity as a function of temperature.The governing equations are an extension of the Navier-Stokes equations with linear Boussinesq's approximation and Buongiorno's nanoscale model (which simulates both heat and mass transfer). The conservation equations are normalized by employing appropriate nondimensional variables. It is assumed that the maximum height of the stenosis is small in comparison with the radius of the artery, and, furthermore, that the radius of the artery and length of the stenotic region are of comparable magnitude. To study the influence of vessel geometry on blood flow and nanoparticle transport, variation in the design and size of the stenosis is considered in the domain. The transformed equations are solved numerically by means of the finite element method based on the variational approach and simulated using the FreeFEM++ code. A detailed grid-independence study is included. Blood flow, heat, and mass transfer characteristics are examined for the effects of selected geometric, nanoscale, rheological, viscosity, and magnetic parameters, that is, stenotic diameter (d), viscoelastic parameter (λ 1 ), thermophoresis parameter (N t ), Brownian motion parameter (N b ), and magnetic body force parameter (M) at the throat of the stenosis and throughout the arterial domain. The velocity, temperature, and nanoparticle concentration fields are also visualized through instantaneous patterns of contours. An increase in magnetic and thermophoresis parameters is found to enhance the temperature, nanoparticle concentration, and skin-friction coefficient. Increasing Brownian motion parameter is observed to accelerate the blood flow. Narrower stenosis significantly alters the temperature and nanoparticle distributions and magnitudes. The novelty of the study relates to the combination of geometric complexity, multiphysical nanoscale, and thermomagnetic behavior, and also the simultaneous presence of biorheological behavior (all of which arise in actual cardiovascular heat transfer phenomena) in a single work with extensive visualization of the flow, heat, and mass transfer characteristics. The simulations are relevant to the diffusion of nano-drugs in magnettargeted treatment of stenosed arterial disease.
K E Y W O R D Sarterial stenosis, finite element method, magnetohydrodynamics, nano-drugs, non-Newtonian blood flow, thermophoresis, Vogel's model