The mafic volcanic association is made up of OIB, E-MORB and N-MORB in the A'nyemaqen Paleozoicophiolites. Compared with the same type rocks in the world, the mafic rocks generally display lower Nb/U and Ce/Pb ratios and some have Nb depletion and Pb enrichment. The OIB are LREE-enriched with (La/Yb) N =5-20, N-MORB are LREE-depleted with (La/Yb) N = 0.41-0.5. The OIB are featured by incompatible element enrichment and the N-MORB are obviously depleted with some metasomatic effect, and E-MORB are geochemically intermediated. These rocks are distributed around the Majixueshan OIB and gabbros in a thickness greater than a thousand meters and transitionally change along the ophiolite extension in a west-east direction, showing a symmetric distribution pattern as centered by the Majixueshan OIB, that is, from N-MORB, OIB and E-MORB association in the Dur'ngoi area to OIB in the Majixueshan area and then to N-MORB, OIB and E-MORB assemblage again in the Buqingshan area. By consideration of the rock association, the rock spatial distribution and the thickness of the mafic rocks in the Majixueshan, coupled with the metasomatic relationship between the OIB and MORB sources, it can be argued that the Majixueshan probably corresponds to an ancient hotspot or an ocean island formed by mantle plume on the A'nyemaqeh ocean ridge, that is the ridge-centered hotspot, tectonically similar to the present-day Iceland hotspot.A'nyemaqen ophiolite zone, OIB, N-MORB and E-MORB association, spatial distribution, Majixueshan ridge-centered hotspot, metasomatism, mantle plume Coexistence of normal mid-ocean-ridge basalts (N-MORB), enriched mid-ocean-ridge basalts (E-MORB) and ocean island basalts (OIB) in the certain tectonic setting has drawn extensive attention and strong interest. Iceland in the North Atlantic Ocean has become a well-known example for the phenomenon. The phenomenon has been thought to be a result of superposition of a hotspot on a ridge (ridge-centered hotspot) [1] or an oceanic island on a ridge (ridge-centered island) [2] or a mantle plume on a ridge (plume on-ridge) [3] , and hotspot-ridge interaction or plume-ridge interaction [4,5] . The spatial superposition and materials interaction between a ridge and a hotspot or an ocean island or a plume cause anomalies of geochemistry, topography, crustal structure, gravity, seismic velocity and bathymetry in the area surrounding a ridge-hotspot [1] .Recent studies have indicated that the coexistence not only occurs in a modern environment like Iceland, but also can be traced into ophiolite zones representing preserved oceanic crust in continental orogenic belts. Hou et al. [6,7] , according to the coexistence of OIB, N-MORB and T-MORB and their specific configuration in space, proposed a paleo-Tethyan mantle plume model to inter-