Micelle–Vesicle Transition by Cleavage of Disulfide Spacer Chain for Gemini Surfactant in Didodecyldimethylammonium Chloride Aqueous Solutions

Mizuhashi, Toshinari; Asakawa, Tsuyoshi; Ohta, Akio

doi:10.5650/jos.ess15083

Cited by 3 publications

(1 citation statement)

References 18 publications

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“…The disulfide bond, which is responsive to reducing agents, strong oxidizers, and light, plays an important role in peptide chains and protein structures. A special class of disulfide-containing surfactants and macromolecules has been synthesized by several researchers. − The amphiphiles containing disulfide bonds have potential applications in functional materials, ,, biomedicine, and drug release. ,, Recently, Li reported a responsive WLM system constructed by disulfide-containing polymers, and the multiresponsiveness of the WLMs improves the therapeutic effect on brain tumors . Nevertheless, the disulfide-containing WLMs constructed by small-molecule surfactants are less documented.…”

Section: Introductionmentioning

confidence: 99%

pH and Redox Dual-Stimulated Wormlike Micelles Based on Cystamine and Conventional Anionic Surfactant

Zhang

Wang

et al. 2019

Langmuir

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Redox-responsive soft materials have attracted considerable concerns throughout the last few decades. Herein, we report the preparation of dual-stimulated wormlike micelles (WLMs) based on N,N,N′,N′-tetramethylcystamine dihydrochloride (TMCDD) and a conventional anionic surfactant, sodium dodecyl sulfate (SDS). The WLMs can be reversibly switched on and off by adjusting pH, resulting from the reversible protonation of TMCDD. Moreover, the WLMs can be destroyed by a redox reaction after addition of dithiothreitol (DTT), originating from the cleavage of the disulfide bonds in TMCDD. The dual responsiveness of the WLMs allowed for the smart control of the “sol–gel” transition or thickening of viscoelastic solutions, and the micelles will have a wider range of applications in the development of functional materials for pharmaceutical or biomedical materials.

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