Micellization of a weakly charged surfactant in aqueous salt solution: Self-consistent field theory and experiments

García, Álvaro González; Timmers, Elizabeth M.; Romijn, N.; Song, Shidong; Sahebali, S Sheen; Tuinier, Remco; Voets, Ilja K.

doi:10.1016/j.colsurfa.2018.10.039

Cited by 12 publications

(7 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…To better understand the origin of the impact of PEG on membrane fluidity, self-consistent mean-field theory (SCFT) 51–53 computations were performed to examine the location of PEG within (supported) bilayers. Since SCFT is principally predictive for liquid components, we focus on the trends exhibited by modelling the interactions of the liquid-like DOPC and not gel-like DPPC membranes of SUVs and CSLBs, with and without DSPE-PEG 2000 (Fig.…”

Section: Resultsmentioning

confidence: 99%

“…Self-consistent mean-field theory (SCFT). Self-consistent mean-field theory (SCFT) [51][52][53] computations were performed on DOPC membranes to examine the location of PEG within (supported) bilayers. SCFT is a theoretical approach involving a lattice discretization scheme, which can be used to predict the equilibrium morphology and spatial composition of self-assembled structures by considering each unimeric building block as a set of chemical units.…”

Section: Preparation Of Fluorescent Cslbsmentioning

confidence: 99%

See 1 more Smart Citation

Impact of poly(ethylene glycol) functionalized lipids on ordering and fluidity of colloid supported lipid bilayers

et al. 2022

Self Cite

View full text Add to dashboard Cite

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Preparation Of Fluorescent Cslbsmentioning

confidence: 99%

Impact of poly(ethylene glycol) functionalized lipids on ordering and fluidity of colloid supported lipid bilayers

et al. 2022

Self Cite

View full text Add to dashboard Cite

show abstract

“…To explain the interactions of the examined ACEIs with Brij 35 micelles, it is necessary to take into account the properties of the applied micelles [ 27 , 28 ]. The monomers of nonionic surfactants do not ionize in aqueous media, so nonionic micelles do not have a charge on the surface [ 29 ].…”

Section: Resultsmentioning

confidence: 99%

Protolytic equilibria of ACE inhibitors in micellar solution of nonionic surfactant Brij 35

2023

View full text Add to dashboard Cite

The acid–base equilibria of six ACE inhibitors (ACEIs), captopril, cilazapril, enalapril, lisinopril, quinapril, and ramipril, were investigated in the presence of micelles of nonionic surfactant Brij 35. The p K a values were potentiometrically determined at 25 °C and at a constant ionic strength (0.1 M NaCl). The obtained potentiometric data were evaluated in the computer program Hyperquad. On the basis of the shift in the p K a values (Δp K a ) determined in micellar media in relation to the p K a values previously determined in “pure” water, the effect of Brij 35 micelles on ACEIs ionization was estimated. The presence of nonionic Brij 35 micelles caused a shift in the p K a values of all ionizable groups of the investigated ACEIs (Δp K a from − 3.44 to + 1.9) while shifting the protolytic equilibria of both acidic and basic groups toward the molecular form. The Brij 35 micelles expressed the most pronounced effect on the ionization of captopril among the investigated ACEIs and stronger effect on the ionization of amino than on the ionization of carboxyl groups. The obtained results suggest that ionizable functional groups of ACEIs are involved in interactions with palisade layer of nonionic Brij 35 micelles, which potentially can be considered in physiological conditions. Distribution diagrams of the investigated ACEIs equilibrium forms as a function of pH indicate that the change in distribution is most strongly expressed in pH range 4–8, which includes biopharmaceutically important pH values. Graphical abstract

show abstract

“…The above examples, obviously, represent only a small slice of possible applications of mesoscale models for surfactants. See also DPD simulations of lipid membranes and vesicles, − SCFT and DPD studies of nanoparticle interactions with lipid bilayers, , SCFT studies of surfactant micellization, − DPD simulations of Ostwald ripening of surfactant-stabilized benzene droplets in water, and many other analyses.…”

Section: Mesoscale Modelingmentioning

confidence: 99%

Mesoscale Modeling of Micellization and Adsorption of Surfactants and Surfactant-Like Polymers in Solution: Challenges and Opportunities

Ginzburg

2022

Ind. Eng. Chem. Res.

View full text Add to dashboard Cite

Surfactants and surfactant-like amphiphilic polymers play important roles in many industrial processes (e.g., home and personal care, laundry, paints and coatings, and biopharmaceuticals). In the past two decades, significant progress has been achieved in understanding and modeling crucial surfactant properties (e.g., critical micellization concentration [CMC], cloud points, adsorption, and stabilization of colloidal particles against flocculation), but many challenges still remain. In this review, several popular data-driven, atomistic, and coarse-grained modeling approaches are described that are used to study surfactant properties. Then, specific examples of how these approaches are used for specific applications are provided. Finally, opportunities and challenges for surfactant theory and modeling are discussed.

show abstract

Micellization of a weakly charged surfactant in aqueous salt solution: Self-consistent field theory and experiments

Cited by 12 publications

References 40 publications

Impact of poly(ethylene glycol) functionalized lipids on ordering and fluidity of colloid supported lipid bilayers

Impact of poly(ethylene glycol) functionalized lipids on ordering and fluidity of colloid supported lipid bilayers

Protolytic equilibria of ACE inhibitors in micellar solution of nonionic surfactant Brij 35

Mesoscale Modeling of Micellization and Adsorption of Surfactants and Surfactant-Like Polymers in Solution: Challenges and Opportunities

Contact Info

Product

Resources

About