Micobactérias não-tuberculosas: diversidade das espécies no estado de São Paulo

Estudo descritivo da freqüência de micobactérias não tuberculosas na Baixada Santista (SP)

“…In this study, using the guidelines established by the American Thoracic Society for the laboratory diagnosis of NTM in nonsterile material (sputum), (1) we found that 80.8% of the individuals in our sample had only one positive culture result, and the diagnosis was therefore unconfirmed. This number is very similar to the 79.8% found in another study, (22) in which 1892 strains of pulmonary origin obtained from nonsterile sites between 1991 and 1997 were evaluated. This shows that there is still a lack of integration between clinical practice and laboratory testing, since there is no guarantee that there will be multiple isolations from which to determine the bacteriological diagnosis.…”

“…(15,18,19) Molecular identification of species was carried out using C-reactive protein method and PCR-restriction (10.4%), which reinforces the data found by other authors regarding the frequency of these species in various regions. (3,8,13,18,22) Unlike the results of a study carried out in 2003, (23) comprising 72 cultures from HIV-positive and HIV-negative individuals suspected of having mycobacteriosis (M. avium, 5.6%; M. kansasii, 2.7%), the data regarding the frequency of NTM in the Baixada Santista region differ from those reported for other regions, in which M. avium was the most frequently isolated species. (13,22) In the present study, M. kansasii was the most common species, highlighting a problem that had not yet been detected in the region.…”

Pulmonary Nontuberculous Mycobacterial Infections in the State of Para, an Endemic Region for Tuberculosis in North of Brazil

“…The impact, magnitude and regional dimension of NTM infections in countries where TB is endemic is hardly known (Gopinath & Singh, 2010), such as the case in Brazil, where most c a s e s o f i n f e c t i o u s N T M h a v e b e e n r e p o r t e d i n t h e s o u t h e a s t e r n r e g i o n a n d , m o r e specifically, in São Paulo (Barreto & Campos, 2000;Ueki et al, 2005;Zamarioli et al, 2008;Pedro et al, 2008). In the Amazon region, North of Brazil, little epidemiological information on this matter is available (da Costa et al, 2009).…”

Avaliação da virulência de isolados suínos de Mycobacterium avium no Brasil caracterizados pelo método de RFLP

“…São patógenos oportunistas e emergentes capazes de causar uma grande variedade de doenças no homem e nos animais (GYLES; THOEN, 1986;INDERLIED et al, 1993;ROIZ et al, 1995;FALKINHAM III, 1996;KOIVULA et al, 2004;UEKI et al, 2005 (SAITO et al, 1990).…”

“…A incidência das micobacterioses humanas -infecções causadas pelas MNTaumentou rapidamente após a emergência da AIDS (síndrome da imunodeficiência humana) em todo o mundo, no início da década de 1980de (INDERLIED et al, 1993FALKINHAM III, 1996;REDDY, 1998;VAN SOOLINGEN et al, 1998;UEKI et al, 2005). Em países desenvolvidos, a incidência de tuberculose é baixa, mas a de infecções não tuberculosas é elevada em pacientes infectados pelo HIV (FALKINHAM III, 1996;REDDY, 1998;KOIVULA et al, 2004), enquanto que, nos países subdesenvolvidos ou em desenvolvimento, a incidência de tuberculose é alta, e a de micobacterioses em pacientes infectados pelo HIV é baixa, provavelmente por virem a óbito por outras causas antes de desenvolverem a doença por M. avium, principal agente etiológico nesses indivíduos (FALKINHAM III, 1996).…”