MicrAnt: Towards Regression Task Oriented Annotation Tool for Microscopic Images

Using virtual microscopy for the development of sampling strategies in quantitative histology and design‐based stereology

“…The importance of proper sampling of sections is elaborated in Figure S3. We found that the tissue composition of the canine soft palate was so heterogeneous that a whole half of the velum had to be sampled using a minimum of 10-15 sections distributed approximately uniformly throughout the complete tissue block to obtain The first step is a whole scan analysis separating the lobules (segmentation to distinguish the sinusoidal ECM from more dense interlobular septa, triads and vessels) (Jirik et al, 2020(Jirik et al, , 2021. Typically, 5 lobules are then selected either manually by the end user or automatically (marked with cyan dots in b).…”

“…The resulting parameters describe the level of ECM structure preservation within individual lobules. It is a two‐step procedure: (b) The first step is a whole scan analysis separating the lobules (segmentation to distinguish the sinusoidal ECM from more dense interlobular septa, triads and vessels) (Jirik et al, 2020, 2021). Typically, 5 lobules are then selected either manually by the end user or automatically (marked with cyan dots in b).…”