The concrete degradation is one of the most serious problems for a dam construct during the normal operation, which determines the dam service life. Hence, it is very important to reduce the extent of the dam concrete degradation for the safety of the dam normal operation. Here, Lijiaxia hydroelectric station is taken as an example, and a comprehensive method to assess the sulphate effect on dam gallery is proposed. Eleven samples in total were taken from three difference locations by the drill bore. The microstructural investigations including X-ray fluorescence spectrometry (XRF), X-ray diffraction (XRD), scanning electron microscope (SEM), and energy dispersive spectroscopy (EDS) were conducted to assess the sulphate attack and the degradation degree. Meanwhile, the water chemical analysis was applied to reveal the mechanism of concrete degradation. The experimental and analysis results indicate that the concrete degradation degree varies with the location of the samples. The components of the concrete change and the content of SO 3 increase dramatically during degradation. Moreover, the mineral facies of the concrete change correspondingly, with the cement paste substituted by the calcite, calcium vitriol, and gypsum. The reinforcement and precaution measures are suggested based on the results of the degradation assessment.