Micro‐arc oxidation and electrophoretic deposition of nano‐grain merwinite (Ca3MgSi2O8) surface coating on magnesium alloy as biodegradable metallic implant

Razavi, Mehdi; Fathi, Mohammadhossein; Savabi, Omid; Vashaee, Daryoosh; Tayebi, Lobat

doi:10.1002/sia.5465

Cited by 25 publications

(13 citation statements)

References 47 publications

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“…An effective technique to reduce the Mg's corrosion rate is surface coating [24]. For a bone implant, the surface coating can also enhance the implant's surface bioactivity (i.e., osteoproductivity), thereby resulting in improved bone-implant integration [25].…”

Section: Introductionmentioning

confidence: 99%

Biodegradable Magnesium Bone Implants Coated with a Novel Bioceramic Nanocomposite

et al. 2020

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Magnesium (Mg) alloys are being investigated as a biodegradable metallic biomaterial because of their mechanical property profile, which is similar to the human bone. However, implants based on Mg alloys are corroded quickly in the body before the bone fracture is fully healed. Therefore, we aimed to reduce the corrosion rate of Mg using a double protective layer. We used a magnesium-aluminum-zinc alloy (AZ91) and treated its surface with micro-arc oxidation (MAO) technique to first form an intermediate layer. Next, a bioceramic nanocomposite composed of diopside, bredigite, and fluoridated hydroxyapatite (FHA) was coated on the surface of MAO treated AZ91 using the electrophoretic deposition (EPD) technique. Our in vivo results showed a significant enhancement in the bioactivity of the nanocomposite coated AZ91 implant compared to the uncoated control implant. Implantation of the uncoated AZ91 caused a significant release of hydrogen bubbles around the implant, which was reduced when the nanocomposite coated implants were used. Using histology, this reduction in the corrosion rate of the coated implants resulted in an improved new bone formation and reduced inflammation in the interface of the implants and the surrounding tissue. Hence, our strategy using a MAO/EPD of a bioceramic nanocomposite coating (i.e., diopside-bredigite-FHA) can significantly reduce the corrosion rate and improve the bioactivity of the biodegradable AZ91 Mg implant.

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Section: Introductionmentioning

confidence: 99%

Biodegradable Magnesium Bone Implants Coated with a Novel Bioceramic Nanocomposite

et al. 2020

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“…They can be made to act as implants or scaffolds that guide regeneration of the surrounding tissues towards formation of new bones and treatment of the area of the injury [13,14]. These scaffolds or implants are usually being either body or surface modified by the use of various coatings or nano-particles to tune their characteristics or to add extra functionalities [15][16][17][18][19].…”

Section: Introductionmentioning

confidence: 99%

Mechanical properties of natural chitosan/hydroxyapatite/magnetite nanocomposites for tissue engineering applications

Heidari

Razavi

Bahrololoom

et al. 2016

Materials Science and Engineering: C

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Chitosan (CS), hydroxyapatite (HA), and magnetite (Fe3O4) have been broadly employed for bone treatment applications. Having a hybrid biomaterial composed of the aforementioned constituents not only accumulates the useful characteristics of each component, but also provides outstanding composite properties. In the present research, mechanical properties of pure CS, CS/HA, CS/HA/magnetite, and CS/magnetite were evaluated by the measurements of bending strength, elastic modulus, compressive strength and hardness values. Moreover, the morphology of the bending fracture surfaces were characterized using a scanning electron microscope (SEM) and an image analyzer. Studies were also conducted to examine the biological response of the human Mesenchymal Stem Cells (hMSCs) on different composites. We conclude that, although all of these composites possess in-vitro biocompatibility, adding hydroxyapatite and magnetite to the chitosan matrix can noticeably enhance the mechanical properties of the pure chitosan.

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“…Razavi et. al [ 31 ] coated calcium magnesium silicate (merwinite) on the magnesium alloy for the first time, by employing the electrophoretic deposition (EPD) technique. They reported a substantial improvement in corrosion resistance of magnesium alloy coated by merwinite compared to akermanite [ 31 ].…”

Section: Resultsmentioning

confidence: 99%

“…al. [ 31 , 32 ] have coated a magnesium alloy substrates with merwinite to enhance its chemical stability and reported a significant increase in its bioactivity compared to the bare magnesium alloy. In addition, the thermal expansion coefficient of magnesium-incorporated calcium silicate compositions (9.87×10 −6 /°C) is close to that of Ti-6Al-4V alloy (9.80×10 −6 /°C)[ 29 ].…”

Section: Introductionmentioning

confidence: 99%

Effect of Tricalcium Magnesium Silicate Coating on the Electrochemical and Biological Behavior of Ti-6Al-4V Alloys

et al. 2015

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In the current study, a sol-gel-synthesized tricalcium magnesium silicate powder was coated on Ti-6Al-4V alloys using plasma spray method. Composition of feed powder was evaluated by X-ray diffraction technique before and after the coating process. Scanning electron microscopy and atomic force microscopy were used to study the morphology of coated substrates. The corrosion behaviors of bare and coated Ti-6Al-4V alloys were examined using potentiodynamic polarization test and electrochemical impedance spectroscopy in stimulated body fluids. Moreover, bare and coated Ti-6Al-4V alloys were characterized in vitro by culturing osteoblast and mesenchymal stem cells for several days. Results demonstrated a meaningful improvement in the corrosion resistance of Ti-6Al-4V alloys coated with tricalcium magnesium silicate compared with the bare counterparts, by showing a decrease in corrosion current density from 1.84 μA/cm2 to 0.31 μA/cm2. Furthermore, the coating substantially improved the bioactivity of Ti-6Al-4Valloys. Our study on corrosion behavior and biological response of Ti-6Al-4V alloy coated by tricalcium magnesium silicate proved that the coating has considerably enhanced safety and applicability of Ti-6Al-4V alloys, suggesting its potential use in permanent implants and artificial joints.

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Micro‐arc oxidation and electrophoretic deposition of nano‐grain merwinite (Ca₃MgSi₂O₈) surface coating on magnesium alloy as biodegradable metallic implant

Cited by 25 publications

References 47 publications

Biodegradable Magnesium Bone Implants Coated with a Novel Bioceramic Nanocomposite

Biodegradable Magnesium Bone Implants Coated with a Novel Bioceramic Nanocomposite

Mechanical properties of natural chitosan/hydroxyapatite/magnetite nanocomposites for tissue engineering applications

Effect of Tricalcium Magnesium Silicate Coating on the Electrochemical and Biological Behavior of Ti-6Al-4V Alloys

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