Micro Bio Processor: a 0.144cc 70uW closed loop platform for body implant electroceutical systems

Kim, Sang Joon; Kang, Jisu; Lee, Wonseok; Kim, Jonghan; Suh, Junyeub; Bae, Chisung; Lee, Hyungwoo; Kim, Jongpal; Jung, Seungchul; Yun, Seok-Ju; Hong, Young Jun; Lee, Hankyu; Lee, Jaechun; Kim, Seong Joong

doi:10.1109/biocas.2019.8918718

Cited by 6 publications

(4 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The prototype's adjustable parameters allow the user or medical professionals to optimize the device performance for specific treatment goals. show the parameter measurements of our prototype compared to those of Livanova VNC [20,21].…”

Section: Resultsmentioning

confidence: 99%

“…The prototype's adjustable parameters allow the user or medical professionals to optimize the device performance for specific treatment goals. Tables 9-12 show the parameter measurements of our prototype compared to those of Livanova VNC [20,21]. The main function of the electroceutical is to connect a microcurrent to the vagus nerve and stimulate it.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

The Development of a New Vagus Nerve Simulation Electroceutical to Improve the Signal Attenuation in a Living Implant Environment

Jo,

Lee,

Jang

et al. 2024

Sensors

View full text Add to dashboard Cite

An electroceutical is a medical device that uses electrical signals to control biological functions. It can be inserted into the human body as an implant and has several crucial advantages over conventional medicines for certain diseases. This research develops a new vagus nerve simulation (VNS) electroceutical through an innovative approach to overcome the communication limitations of existing devices. A phased array antenna with a better communication performance was developed and applied to the electroceutical prototype. In order to effectively respond to changes in communication signals, we developed the steering algorithm and firmware, and designed the smart communication protocol that operates at a low power that is safe for the patients. This protocol is intended to improve a communication sensitivity related to the transmission and reception distance. Based on this technical approach, the heightened effectiveness and safety of the prototype have been ascertained, with the actual clinical tests using live animals. We confirmed the signal attenuation performance to be excellent, and a smooth communication was achieved even at a distance of 7 m. The prototype showed a much wider communication range than any other existing products. Through this, it is conceivable that various problems due to space constraints can be resolved, hence presenting many benefits to the patients whose last resort to the disease is the VNS electroceutical.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

The Development of a New Vagus Nerve Simulation Electroceutical to Improve the Signal Attenuation in a Living Implant Environment

Jo,

Lee,

Jang

et al. 2024

Sensors

View full text Add to dashboard Cite

show abstract

“… 55 When a high concentration of Vit C was used, MPD of the fuel cell using BP/Vit B 12 catalyst was 57.7 ± 4.02 μW cm −2 , while that using pristine BP catalyst was 25.6 ± 2.35 μW cm −2 . Since the commercial pacemaker typically consumes a power of 10 to 15 μW and the recently reported implantable neural electroceutical system needs a power of 70 μW, the produced power range of the Vit C fuel cells developed in this study is appropriate for body‐implantable energy devices to alter the conventionally considered primary batteries 56,57 …”

Section: Resultsmentioning

confidence: 99%

“…Since the commercial pacemaker typically consumes a power of 10 to 15 μW and the recently reported implantable neural electroceutical system needs a power of 70 μW, the produced power range of the Vit C fuel cells developed in this study is appropriate for body-implantable energy devices to alter the conventionally considered primary batteries. 56,57 It is now necessary to investigate whether the flexible membraneless Vit C fuel cells using BP/Vit B 12 catalyst can work well even in actual conditions. With the target, Figure 8 shows the polarization curves whose samples are measured with orange juice and raw orange as fuels, while the paper-based cell kit and membraneless cell kit are used (Scheme 1B,C).…”

Section: Performance Of Bp/vit B 12 In Vit C Fuel Cellsmentioning

confidence: 99%

Paper‐based flexible membraneless fuel cells using vitamins as both anodic catalyst and fuel

Jeon

Chung

et al. 2022

Intl J of Energy Research

View full text Add to dashboard Cite

Direct liquid fuel cell (DLFC) and membraneless fuel cell using the anode consisting of buckypaper (BP) and vitamin B 12 (Vit B 12 ) (BP/Vit B 12 ) is introduced in physiological condition, while vitamin C (Vit C) is used as anodic fuel. Due to the high sensitivity of Vit B 12 and the inherent feature of BP, the onset potential for the oxidation reaction of Vit C catalyzed by BP/Vit B 12 is À0.1 V (vs Ag/AgCl), and its anodic current density measured at 0.3 V (vs Ag/AgCl) is 1.82 mA cm À2 even in a low Vit C concentration (10 mM). Regarding performance in fuel cells, maximum power density (MPD) of Vit C fuel cell containing membrane and Pt-based air cathode is 0.62 ± 0.067 mW cm À2 in 0.01 M Vit C, and this is 3.1 times higher than that of fuel cell containing pristine BP. In addition, in a paper-based flexible membraneless fuel cell using BP/bilirubin oxidase as cathode and the concentration of cerebrospinal fluid within the human body (0.35 mM Vit C), its MPD is 57.7 ± 4.02 μW cm À2 . This means this suggested Vit C fuel cell system can replace the conventional primary batteries considered as the power source of implantable sensors and stimulation devices to treat neurological disorders.

show abstract

A Compact Base Station System for Biotelemetry and Wireless Charging of Biomedical Implants

Lee

Kang

Lee

et al. 2019

2019 IEEE Asia-Pacific Microwave Conference (APMC)

View full text Add to dashboard Cite

Micro Bio Processor: a 0.144cc 70uW closed loop platform for body implant electroceutical systems

Cited by 6 publications

References 3 publications

The Development of a New Vagus Nerve Simulation Electroceutical to Improve the Signal Attenuation in a Living Implant Environment

The Development of a New Vagus Nerve Simulation Electroceutical to Improve the Signal Attenuation in a Living Implant Environment

Paper‐based flexible membraneless fuel cells using vitamins as both anodic catalyst and fuel

A Compact Base Station System for Biotelemetry and Wireless Charging of Biomedical Implants

Contact Info

Product

Resources

About