Micro-Environment mapping of mole fraction inspired contrasting charged aqueous gemini micelles: A drug solubilization/release study

Micellization, aggregation, interaction, and solubilization behaviors of mixed solutions of cationic gemini and nonionic surfactants

“…The organic compounds solubilize in and/or near the core of the micelles, where the hydrophobic chain portions are located. Different possible localization sites are available in the micelle systems for the solubilization of organic compounds (Patel, Singh, Parikh, Chavda, Ray, et al, 2022). The molecular structure and polarity of a compound decide which location sites are suitable in the micellar system.…”

Deep Eutectic Solvent/Surfactant-Engineered GO@TiO2 Advanced Material for Sustained and Ultrafast Adsorption of Hazardous Dye from Contaminated Aqueous Environment

“…Surfactants are preferred as modification agents in the provided context due to their straightforward synthesis procedure, capacity to enhance crystallinity and thermal resistance, prevention of agglomeration, and facilitation of surface area expansion and regulated porosity in the modified material. − Among various charge types, cationic surfactants have demonstrated superiority as modifiers, outperforming other classes of materials. Cationic surfactants effectively adsorb onto the carboxyl groups of GO through electrostatic attraction, leading to the formation of insoluble complex salts .…”

Synergistic Self-Assembly in a Surface-Active Ionic Liquid and an Anionic Surfactant Mixed System: A Comprehensive Physicochemical Analysis

“…7−9 The mixed aggregates obtained by oppositely charged Gemini surfactants possess higher solubilization capabilities and are used for the solubilization of polycyclic aromatic hydrocarbons (PCAHs) 10−12 and anticancer drugs. 13 The mixed aggregates of cationic Gemini surfactants and negatively charged bile salts are also employed for the solubility enhancement of PCAHs where individual constituting surfactants failed. 14 However, the biggest challenge of mixing oppositely charged surfactants is the formation of precipitates that lower the stability and performance-based properties of mixed aggregates.…”

“…By careful adjustment of the composition and proportion of surfactants, it is possible to precisely modify the characteristics of such formulations. Such mixed aggregates find widespread applications due to their exceptional surface activity, emulsification capabilities, and improved cleansing power that can be used for oil recovery processes as well. , Similarly, mixing of surfactants with opposing charges may enhance the effectiveness of mixed aggregates that find applications in fields ranging from detergency, dispersion, cosmetics, pharmaceuticals, food processing, wetting, and oil recovery. − The mixed aggregates obtained by oppositely charged Gemini surfactants possess higher solubilization capabilities and are used for the solubilization of polycyclic aromatic hydrocarbons (PCAHs) − and anticancer drugs . The mixed aggregates of cationic Gemini surfactants and negatively charged bile salts are also employed for the solubility enhancement of PCAHs where individual constituting surfactants failed .…”