“…H o w ev er ev idence th a t n o n p a th o g e n s b elo n ging to th e b a c te ria [2,10,12,25,34,37,47,54], a c tin o m y cetes [10,25,29,34,45], actin o p lan es [21,32], phyco m y cetes [27,31,44], asco m y cetes an d im p erfect fu n g i [10,25,34,38,47,50,57] T h ese o b serv atio n s in d ic a te t h a t we lack m odel te s t sy stem s a p p ro p ria te b o th for c o m p a ra tiv e stu d ies and in v e stig a tio n o f th e b io c h e m istry o f d e g ra d a tio n . T h e p re se n t w ork is an e n d e a v o u r to o vercom e th is deficiency, b eg in n in g w ith the d ev elo p m en t o f a m eth o d for sterilisin g th e k e ra tin s u b s tra te th a t avoids d e n a tu ra tio n .…”