Micro-Raman spectroscopy of mixed cancer cell populations

Characterization of the distribution, polymorphism, and stability of nimodipine in its solid dispersions in polyethylene glycol by micro-Raman spectroscopy and powder x-ray diffraction

“…8 Since the FT-Raman and micro-Raman techniques have begun to be used in the study of pharmaceutics only recently, a limited number of studies currently exist in the literature. [28][29][30][31][32][33][34] Before now, mapping has been used in only 1 study of solid dispersion systems. 22 The preparation and storage conditions of the solid dispersions play a critical role, as changes may alter the dissolution characteristics of the active ingredients over time.…”

Cellular discrimination using in vitro Raman micro spectroscopy: the role of the nucleolus

“…Numerous studies over the last few years have investigated the capability of Raman micro spectroscopy to differentiate between cancerous cell lines; Crow et al 39 41 All those studies demonstrated that Raman micro spectroscopy, coupled with multivariate statistics, is able to distinguish between different cell lines with a high specificity and sensitivity. However, the basis of the differentiation was not elucidated in terms of the subcellular regions.…”

Raman spectroscopic mapping for the analysis of solar radiation induced skin damage

“…Every year, there are more new cases of skin cancer than the combined incidence of cancers of breast, lung and colon 2 . However, if diagnosed at an early stage, the prognosis is quite good, highlighting the demand for improved rapid screening and diagnostic technologies [3][4][5] . Solar irradiation, as one of the most important environmental stressors, has long been known to be the main etiological cause of skin cancers and accelerated skin ageing.…”

“…Moreover, excisional biopsy of delicate organs associated with the central nervous or vascular systems could be hazardous. An ideal diagnostic test for early disease detection should be rapid and non-invasive 3,7 .…”