Vortex spinning is a novel technology which produces short-staple yarns by utilizing high-speed swirling airflow. The structure of the spindle piays an important role in vortex spinning in terms of its effect on the resuiting yarn properties, ln this paper, a twodimensionai fluid-structure interaction (FSI) modei for the fiber/air two-phase flow is presented to design the two spindle parameters-the spindle cone angle and spindle diameter by evaluating their effects on the fiber dynamics in the flow fleld inside the tnnsting system and the resulting yarn tenacity. The coupling between the fiber and airflow is solved and the motional characteristics of the fiber are obtained. It is found that the fiber moves downstream in a varying wavy shape and its spreaded trailing portion is then in a heiical motion to form the yarn. The results also show that the increase of the spindle cone angle has a negative effect on the tenacity of the produced vortex yarn. The increased spindle diameter gives rise to the decreased vortex yarn tenacity. The numericai results can provide an explanation for the experimental results reported by previous studies.