Microalbuminuria and serum procalcitonin levels following oesophagectomy

Abstract

Fig. 2. The progress of serum PCT levels from arrival on the ICU (T 0 ) to T 72 h postoperatively. Data are presented as minimum, maximum, 25±75% percentile and median. For statistical analysis Wilcoxon's test was used, **P < 0.001 vs. T 0 .

Procalcitonin levels do not predict mortality following major abdominal surgery

“…2 The significantly higher PCT levels in the non-survivor group may be the result of a clinically undetectable bacterial translocation during 1082 CANADIAN JOURNAL OF ANESTHESIA FIGURE The progress of serum procalcitnonin (PCT) levels from arrival on intensive care unit (t 0 ) to 72 hr (t 72 ) postoperatively in survivors and non-survivors. Data are presented as boxes and whisker plots.…”

“…Anesthesia with propofol and remifentanil has been reported in elective surgery and well prepared myasthenic patients. 2 An 80-yr-old male myasthenic patient (stage IIb Ossermann), with a previous history of prolonged neuromuscular blockade after anesthesia, was scheduled for emergency surgery for gangrenous perforated cholecystitis with peritonitis. Considering the patient's critical condition, the surgeons suggested a laparoscopic technique.…”

Prophylactic N-acetylcysteine decreases serum CRP but not PCT levels and microalbuminuria following major abdominal surgery. A prospective, randomised, double-blinded, placebo-controlled clinical trial

“…Our preliminary studies showed a mean PCT at 24 h postoperatively of 5.3±4.3 ng/ml -1 [22]. In a previous descriptive study we found that PCT >2.8 ng/ml -1 showed an 84% sensitivity of predicting mortality [12].…”

“…Unfortunately, real pre-treatment of septic patients cannot be achieved in clinical practice. However, we found that major abdominal surgery, which carries a considerable risk of morbidity and mortality, initiates an inflammatory response as detected by increased PCT, CRP and M:Cr [22]. Therefore, we decided to pre-treat highrisk patients undergoing elective surgery with shortterm NAC infusion and assess its effect on the early postoperative course of inflammation.…”

“…Procalcitonin, an infection-induced protein, has been shown to be one of the most sensitive and specific early markers of sepsis [8]. We have previously described the normal kinetics of PCT following uncomplicated oesophagectomy [22]. Recent papers have reported that increased PCT levels were found after different types of surgery, even if bacterial infection was not evident [6,9,33].…”