Microalgae have higher nutritional value as they are abundant in protein, carbohydrates, lipids, and vitamins. Hence, they play several important roles in aquaculture and are known as a major source of the food chain for aquaculture organisms. Furthermore, they are also used indirectly or directly by humans as food supplements and medicines to improve health by strengthening the immune system. Microalgae are used as biocontrol agents because they have biocidal properties, produce biomolecules (beta carotene, PUFA, and astaxanthin), wastewater, are a renewable resource of biofuel, and are used in wastewater treatment. Due to the overexploitation of wild fish and pollution, aquaculture faces serious issues. Eco- friendly methods are required to overcome this problem, so, microalgae are in practicing, that control the water pollution. Fishmeal is a rich source of protein in aquaculture but it is decreasing over time and has become cost-effective, so, to solve the problem, microalgae are used to replace the fishmeal which (microalgae as aquafeed) is cheap and not required large area to grow. Microalgae are seemed to be very useful in the growth enhancement of aquatic organisms.