Microarray analysis of the effect of Cowpea (<i>Vigna unguiculata</i>) phenolic extract in bovine peripheral blood

Adjei‐Fremah, Sarah; Jackai, L. E. N.; Schimmel, Keith; Worku, Mulumebet

doi:10.1080/09712119.2016.1264305

Cited by 14 publications

(8 citation statements)

References 43 publications

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“…Pulses are a vital source of plant-based proteins and amino acids for people around the globe and may be eaten as part of a healthy diet to address obesity, as well as to prevent and help manage chronic diseases such as diabetes, coronary conditions and cancer; they are also an important source of plant-based protein for animals [6,117]. In a study of the phenolic content and antioxidant properties of selected cowpea varieties tested in bovine peripheral blood.…”

Section: Effects Of Water Stress On Grain Nutrient Content and Phytocmentioning

confidence: 99%

“…Adjei-Fremah et.al. [118] reported that, the potential of cowpea polyphenols to reduce oxidative stress in livestock production is high which is a positive indication for human health improvement. Viets [119] and Alam [120] reported that, drought reduces both nutrient uptake by the roots and transport from the roots to the shoots, because of restricted transpiration rates and impaired active transport and membrane permeability, the decline in soil moisture also results in a decrease in the diffusion rate of nutrients in the soil to the absorbing root surface [121,122].…”

Section: Effects Of Water Stress On Grain Nutrient Content and Phytocmentioning

confidence: 99%

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Genetic Variability for Flowering Time, Maturity and Drought Tolerance in Cowpea [Vigna unguiculata (L.) Walp.]: A Review Paper

Alidu

2019

JAERI

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Background: Cowpea plays a critical role in the lives of millions of people in Africa and other parts of the developing world, where it is a major source of dietary protein that nutritionally complements staple low-protein cereal and tuber crops. It is a valuable and dependable commodity that produces income for farmers and traders. Objective: To review related research work on the genetic variability for time to flowering, maturity and drought tolerance in cowpea. Data Source: Searches were made from the following databases and archives; International Institute of Tropical Agriculture (IITA), The Essential Electronic Agricultural Library (TEAL), Access to Global Online Research in Agriculture (AGORA) (FAO), AGRICOLA (National Agricultural Library), AGRIS - Agricultural Sciences and Technology (FAO), CAS - Chemical Abstracts (ACS), DOAJ - Directory of Open Access Journals, CABI, Euphytica, Elsevier, Research Alert, Scopus and CGIAR, Plant Genetics and Breeding Database, Crop Science Database, Plant Genetics and Breeding Database, data base repositories, using the terms “genetic variability”, “drought”, “tolerance”, “ time to flowering and maturity”, and “cowpea” individually or in combination to identify literature published in English language between January 1990 to January 2018. Methods: The review was carried out using the above search terms. Research papers were critically reviewed, relevant data extracted, and a narrative synthesis was conducted to determine the relevant papers. Results: In all 150 papers met the inclusion criteria. Collections were from varied background; Sub-Saharan Africa, Asia, Europe, and Latin Americas. Conclusion: Despite research studies on cowpea and drought, there appears to be limited such research findings on the time to flowering, and maturity in relations to drought tolerance in cowpea in Ghana, suggesting more research in this part of the world.

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Section: Effects Of Water Stress On Grain Nutrient Content and Phytocmentioning

confidence: 99%

Section: Effects Of Water Stress On Grain Nutrient Content and Phytocmentioning

confidence: 99%

Genetic Variability for Flowering Time, Maturity and Drought Tolerance in Cowpea [Vigna unguiculata (L.) Walp.]: A Review Paper

Alidu

2019

JAERI

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“…Epigallocatechin-3-gallate, a flavonoid found in green tea, has been shown to inhibit NF-κB activation induced by many proinflammatory stimuli [67]. Recently, there is a great interest in feed polyphenols due to their antioxidant capacity, inflammatory and immunomodulatory properties and their possible beneficial implications on animal health and production [7,54,68,69,79].…”

Section: Plant Polyphenolsmentioning

confidence: 99%

Molecular Genetics and Genome Biology of Goats

Ekwemalor¹,

Adjei‐Fremah²,

Asiamah³

et al. 2018

Goat Science

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Information on goat genome has led to a better understanding of the genetics of goats, its response to infection and the underlying immune response mechanism. Natural productbased therapeutic can therefore be utilized to target genes important for goat immunity. In this chapter, we have summarized the effect of diet and dietary supplements as immune modulators in goats. These modulators affect the expression of genes and secreted proteins associated with innate and adaptive immune response and homeostasis. Probiotics, mushroom extracts, plant polyphenol extracts, Sericea lespedeza (SL) and cowpea diet affect key molecular pathways including Toll-like receptor (TLR) pathway, Wnt signaling pathway and cytokine-mediated signaling pathway. Results from various studies reviewed in this chapter suggest that utilization of dietary immunomodulators has beneficial effects on goat health and production.

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“…Reverse transcription was performed using Oligo (dT) primers with 2 ug of the total RNA from each treatment group using a Complementary DNA (cDNA) RETRO script Kit (Ambion Inc., Austin, TX) following the manufacturer's instructions as previously described by Adjei-Fremah et al, 2016c. The cDNA products were measured for purity and concentration using the Nanodrop spectrophotometer (NanoDrop Technologies).…”

Section: Real-time Pcrmentioning

confidence: 99%

Evaluation of the Effect of Probiotic Administration on Gene Expression in Goat Blood

Ekwemalor

Asiamah

Osei

et al. 2017

JMBR

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The objective of this study was to assess the molecular impact of probiotic administration on genes involved in homeostasis and immunity in goat blood. Following initial screening for infection, one-week post weaning, female SpanishXBoer goats were drenched daily with the recommended doses of FASTtrak microbial pack (Conklin Company Inc., Shakopee, MN) in 10 mL sterile water over an 8-week period. The control group were given sterile water. Blood samples were collected weekly. Total RNA was isolated from blood collected at the beginning of the study (week 0) and at the end of the study (week 8) using Tri-reagent and then reverse-transcribed to cDNA using the Ambion-Retroscript kit. Quantification of genes was performed in the CFX96 Probiotic treatment had no effect on body weight, body condition, fecal egg count and RNA concentration (p>0.05). Packed cell volume and FAMACHA scores were significantly improved by probiotic administration. Results from RT-PCR showed increased expression of genes in innate and adaptive immune response, cytokine and Wnt pathways in response to probiotics. Probiotics induced the expression of 32 genes involved in innate and adaptive immune response inflammatory cytokines, and 48 genes involved in the Wnt signaling pathway. This study provides evidence for a systematic effect of oral probiotic administration on expression of genes involved in immunity and homeostasis in goat blood.

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Microarray analysis of the effect of Cowpea (Vigna unguiculata) phenolic extract in bovine peripheral blood

Abstract: View related articles View Crossmark data Citing articles: 4 View citing articles Microarray analysis of the effect of Cowpea (Vigna unguiculata) phenolic extract in bovine peripheral blood

Cited by 14 publications

References 43 publications

Genetic Variability for Flowering Time, Maturity and Drought Tolerance in Cowpea [Vigna unguiculata (L.) Walp.]: A Review Paper

Genetic Variability for Flowering Time, Maturity and Drought Tolerance in Cowpea [Vigna unguiculata (L.) Walp.]: A Review Paper

Molecular Genetics and Genome Biology of Goats

Evaluation of the Effect of Probiotic Administration on Gene Expression in Goat Blood

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