Microaspiration in Infants with Laryngomalacia

Midulla, Fabio; Guidi, Roberto; Tancredi, Giancarlo; Quattrucci, Serena; Ratjen, Félix; Bottero, Sergio; Vestiti, Katia; Francalanci, Paola; Cutrera, Renato

doi:10.1097/00005537-200409000-00017

Cited by 25 publications

(15 citation statements)

References 15 publications

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“…Fortunately, these were not related to the risks of general anesthesia. Laryngomalacia is the most common congenital laryngeal anomaly and the most frequent cause of stridor in infants (6)(7)(8)(9)(10)(11), and is usually a benign condition that disappears as the child grows up, usually without requiring treatment (11). Laryngomalacia is a condition in which the laryngeal tone is weak, which results in dynamic prolapse of supraglottic tissue into the airway, causing inspiratory stridor and airway obstruction (10).…”

Section: Discussionmentioning

confidence: 99%

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General anesthesia for a patient with deletion 6q syndrome in addition to laryngomalacia undergoing dental treatment

2008

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Chromosome 6 deletions are very rare (1,2), and deletion 6q syndrome is clinically characterized by mental and/or neuromotor retardation and microcephaly (3). Other alterations frequently observed are decreased biparietal diameter, hypertelorism, hypotelorism, absent eyebrows, prominent eyes with ptosis, receding chin, dysmorphic ears, large extremities, prominent nasal bridge, long philtrum, epicthus, strabismus, and micrognathia (3-5). Laryngomalacia is the most common congenital laryngeal anomaly and the most frequent cause of stridor in infants (6-11). We report the case of a 14-yearold male patient with both deletion 6q syndrome and laryngomalacia, who we treated for multiple dental caries. He had a medical history of tracheotomy at age 11 years for laryngomalacia, and has suffered from epileptic attacks and aspiration pneumonia over the last 2 and 6 years, respectively. Since he was mentally retarded and in a poor respiratory state, dental treatment under general anesthesia was scheduled in our hospital. General anesthesia was induced and maintained using 30% nitrous oxide and 1-3% sevoflurane in oxygen through the tracheotomy tube. Pre-and intraoperative endotracheal suction improved the condition of both lungs markedly and the procedures were uneventful and completed in 2 h and 58 min. (J. Oral Sci. 50, [493][494][495] 2008)

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Section: Discussionmentioning

confidence: 99%

“…Laryngomalacia is a condition in which the laryngeal tone is weak, which results in dynamic prolapse of supraglottic tissue into the airway, causing inspiratory stridor and airway obstruction (10). Its distinctive features are collapse of the arytenoids, epiglottis and aryepiglottic folds, usually during the inspiratory phase (11).…”

Section: Discussionmentioning

confidence: 99%

General anesthesia for a patient with deletion 6q syndrome in addition to laryngomalacia undergoing dental treatment

2008

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“…Thus, whether laryngomalacia is primarily an anatomical abnormality or whether it is due to delayed neuromuscular development remains under debate. Laryngomalacia is frequently associated with gastro-esophageal reflux, and infants with laryngomalacia may have episodes of micro-aspiration as well [3][4][5] . The natural history of laryngomalacia is characterized by an onset of inspiratory stridor usually within the first 4-6 weeks of life; the infant's voice and cry are normal.…”

Section: Laryngomalaciamentioning

confidence: 99%

Utility of Pediatric Flexible Bronchoscopy in the Diagnosis and Treatment of Congenital Airway Malformations in Children

Yin¹,

Yuan²,

Zhong³

et al. 2012

Global Perspectives on Bronchoscopy

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“…Although the stridor associated with laryngomalacia usually disappears during the first year of life, laryngomalacia is associated with other bronchial anomalies in 15% of cases and associated clinical symptoms related to gastro-oesophageal reflux and microaspiration may occur [87,88].…”

Section: Paediatric Bronchologymentioning

confidence: 99%

Paediatrics in Vienna: Table 1—

Brand¹,

Ratjen²,

Aurora³

et al. 2010

Eur Respir J

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The aim of this article is to describe the paediatric highlights from the 2009 European Respiratory Society Annual Congress in Vienna, Austria. The best abstracts from the seven groups of the Paediatric Assembly (asthma and allergy, respiratory epidemiology, cystic fibrosis, respiratory physiology, respiratory infections and immunology, neonatology and paediatric intensive care, and bronchology) are presented alongside findings from the current literature.

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Microaspiration in Infants with Laryngomalacia

Abstract: Infants with laryngomalacia may have episodes of microaspiration. BAL performed during FFB to evaluate stridor may add helpful therapeutic information without increasing the risks of the procedure.

Cited by 25 publications

References 15 publications

General anesthesia for a patient with deletion 6q syndrome in addition to laryngomalacia undergoing dental treatment

General anesthesia for a patient with deletion 6q syndrome in addition to laryngomalacia undergoing dental treatment

Utility of Pediatric Flexible Bronchoscopy in the Diagnosis and Treatment of Congenital Airway Malformations in Children

Paediatrics in Vienna: Table 1—

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