Microbes and Mental Illness: Past, Present, and Future

Bransfield, Robert C.; Mao, Charlotte; Greenberg, Rosalie

doi:10.3390/healthcare12010083

Cited by 3 publications

(1 citation statement)

References 442 publications

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“…Addressing these issues through comprehensive support systems and effective training is crucial to ensure the well-being and safety of healthcare workers during the pandemic. [23][24][25]…”

Section: Discussionmentioning

confidence: 99%

Effect of educational intervention on the use of personal protective equipment in nursing staff

Angeloni,

Santos Junior,

Ferreira

et al. 2024

Rev Prev Infec e Saúde

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Introduction: In the context of the COVID-19 pandemic, specific care in the use of Personal Protective Equipment (PPE) is crucial for patient care. Aim: To evaluate the impact of an educational intervention on the self-reported use of PPE by nursing professionals. The primary question guiding this research was: What is the effect of an educational intervention on the self-reported use of PPE by nursing professionals? Design: This quasi-experimental study used a before-and-after design and involved 98 nursing professionals. Results: It was found that 78.30% of nursing technicians reported absences from work due to COVID-19. Among these professionals, 82.27% reported having access to PPE during the pandemic, yet only 78.4% had received training on its usage. Notably, before the educational intervention, 53.2% of nursing technicians and 57.8% of nurses correctly performed PPE placement. After the intervention, these figures changed to 45.5% and 36.8%, respectively. Regarding the correct sequence of PPE removal, before the intervention, 32.9% of nursing technicians and 57.8% of nurses reported accuracy; these numbers slightly changed post-intervention to 34.1% and 52.6%, respectively. Implications: The educational intervention resulted in significant improvements in the correct removal of PPE, particularly among technical-level professionals. This outcome underscores the importance of ongoing training programs, tailored to the specific needs and experience levels of healthcare professionals, to enhance adherence to safety practices and optimize protection in high-risk environments.

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“…Addressing these issues through comprehensive support systems and effective training is crucial to ensure the well-being and safety of healthcare workers during the pandemic. [23][24][25]…”

Section: Discussionmentioning

confidence: 99%

Effect of educational intervention on the use of personal protective equipment in nursing staff

Angeloni,

Santos Junior,

Ferreira

et al. 2024

Rev Prev Infec e Saúde

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Neurobartonelloses: emerging from obscurity!

Bush,

Robveille,

Maggi

et al. 2024

Parasites Vectors

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Background Bartonella species are fastidious, intracellular bacteria responsible for an expanding array of human pathologies. Most are considered to be transmitted by direct inoculation with infected bodily fluids from a mammalian reservoir species or vector-transmitted through a variety of arthropod species and their excrement. However, there are mounting reports of infection in the absence of documented animal or vector contact. A variety of Bartonella species have been documented in conditions affecting both the peripheral and central nervous systems. More common conditions, including neuroretinitis, are often associated with Bartonella henselae. However, Bartonella quintana, the agent of trench fever, as well as emerging pathogens related to rodent reservoir species, B. grahamii and B. elizabethae, have also been documented. Encephalitis and encephalopathy, also most often associated with B. henselae, have been reported with B. quintana, B. washoensis (ground squirrels) and B. vinsonii subsp. vinsonii (voles) infections. Bartonella infections have also been associated with peripheral neuropathies, such as cranial nerve paresis and neuropathic pain, including infection with less commonly encountered species such as Bartonella koehlerae. Recently, molecular diagnostic testing revealed that DNA from Bartonella spp. was found to be more prevalent in blood of patients with neuropsychiatric disorders such as schizophrenia and psychoses compared to healthy controls. Methods A systematic literature search was conducted on PubMed, Google Scholar and Web of Science. Search terms included Bartonella and specific neurological conditions and focused on peer-reviewed case reports published after 2012 pursuant to a prior review, with limited exceptions for conditions not previously covered. Published diagnostic testing, serology, molecular testing or pathology, were necessary for inclusion, except for one case which had clinical and epidemiological evidence consistent with diagnosis along with follow-up. Results Neurobartonelloses included neuralgic amyotrophy, complex regional pain syndrome, chronic inflammatory demyelinating polyneuropathy, cranial nerve paralysis, Guillain-Barré syndrome, peripheral vasculitic polyneuropathy, acute transverse myelopathy, neuroretinitis, encephalitis/encephalopathy, cerebral vasculitis/aneurysm and neuropsychiatric conditions. Conclusions The breadth of reported symptoms and clinical syndromes associated with an increasing number of Bartonella species continues to expand. Increased clinical awareness of this important zoonotic pathogen is necessary to advance One Health among the medical and veterinary communities. Graphical Abstract

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The Impact of Infectious Diseases on Psychiatric Disorders: A Systematic Review

Okobi,

Ayo-Farai,

Tran

et al. 2024

Cureus

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The complex connection between some infectious illnesses and some psychiatric disorders is an important area of study, with infections known to cause a diverse range of psychiatric symptoms. This association poses significant challenges for physicians in differentiating between mental illnesses induced by infections and those stemming from underlying psychiatric conditions. This study systematically synthesizes literature from various databases that explain the relationship between certain infectious diseases and specific psychiatric disorders. The systematic review explores mechanisms such as neuroinflammation, direct central nervous system (CNS) infection, and the interaction between the immune system and psychiatric conditions. The study examines various infectious pathogens, including viruses, bacteria, parasites, prion diseases, and fungi. An analysis of these findings is presented in the study's discussion section, along with a review of therapeutic methods such as drug use and psychological treatment. The review emphasizes the need for multidisciplinary teamwork and thorough clinical examinations in managing psychiatric symptoms caused by infections. It also highlights the significant role of public health measures in mitigating the impact of psychiatric diseases related to infectious illnesses. The study finds that current therapeutic methods include pharmacological and psychological treatments, which can effectively manage these conditions. The study has concluded that psychiatric manifestations are prevalent across various infectious diseases, including those caused by viruses, bacteria, parasites, and fungi. Key mechanisms identified include neuroinflammation, direct infection of the CNS, and the immuno-psychiatric interface, all of which contribute to the development of psychiatric symptoms. The future of managing these complex conditions lies in a comprehensive approach that combines clinical, therapeutic, and public health strategies.

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Microbes and Mental Illness: Past, Present, and Future

Cited by 3 publications

References 442 publications

Effect of educational intervention on the use of personal protective equipment in nursing staff

Effect of educational intervention on the use of personal protective equipment in nursing staff

Neurobartonelloses: emerging from obscurity!

The Impact of Infectious Diseases on Psychiatric Disorders: A Systematic Review

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