Microbial antioxidant defense enzymes

Staerck, Cindy; Gastebois, Amandine; Vandeputte, Patrick; Calenda, Alphonse; Larcher, Gérald; Gillmann, Louiza; Papon, Nicolas; Bouchara, Jean‐Philippe; Fleury, Maxime

doi:10.1016/j.micpath.2017.06.015

Cited by 202 publications

(126 citation statements)

References 131 publications

Supporting

Mentioning

121

Contrasting

Unclassified

Order By: Relevance

“…The antioxidant defensive system of the microbe will be induced by these heavy ions to reduce the content of heavy metals within the cells by facilitating their efflux. [ 177 ] Many ion carriers, such as desferrioxamine E, desferrioxamine B, and coelichelin, have been demonstrated to reduce heavy metals such as Cd 2+ . These ion carriers may be responsible for maintaining metal homeostasis.…”

Section: Mechanisms Of Microbe‐mediated Mineralizationmentioning

confidence: 99%

Microbe‐Mediated Extracellular and Intracellular Mineralization: Environmental, Industrial, and Biotechnological Applications

et al. 2020

View full text Add to dashboard Cite

Bacteria play an important role in the calcification process of natural minerals and within organisms ( Table 1). It is Microbe-mediated mineralization is ubiquitous in nature, involving bacteria, fungi, viruses, and algae. These mineralization processes comprise calcification, silicification, and iron mineralization. The mechanisms for mineral formation include extracellular and intracellular biomineralization. The mineral precipitating capability of microbes is often harnessed for green synthesis of metal nanoparticles, which are relatively less toxic compared with those synthesized through physical or chemical methods. Microbe-mediated mineralization has important applications ranging from pollutant removal and nonreactive carriers, to other industrial and biomedical applications. Herein, the different types of microbe-mediated biomineralization that occur in nature, their mechanisms, as well as their applications are elucidated to create a backdrop for future research.

show abstract

Section: Mechanisms Of Microbe‐mediated Mineralizationmentioning

confidence: 99%

Microbe‐Mediated Extracellular and Intracellular Mineralization: Environmental, Industrial, and Biotechnological Applications

et al. 2020

View full text Add to dashboard Cite

show abstract

“…Oxidative stress sensitively reacts via ROS and induces lipid peroxidation by deformation of polyunsaturated fatty acids, which are important components of cell membranes; the marker that represents this condition is MDA [34]. On the other hand, the body has an efficient antioxidant defense system to protect from oxidative stress, consisting of antioxidant enzymes such SOD, catalase, and GPx [35]. Regular exercise training can increase antioxidant capacity [36,37].…”

Section: Discussionmentioning

confidence: 99%

Effects of Regular Taekwondo Intervention on Oxidative Stress Biomarkers and Myokines in Overweight and Obese Adolescents

Roh

Cho

2020

IJERPH

View full text Add to dashboard Cite

Purpose: Regular exercise can alleviate oxidative stress related to obesity and can induce secretion of myokines that are involved in the regulation of metabolic homeostasis. There are no studies examining changes in these variables as a result of Taekwondo training intervention. We aimed to investigate the effect of Taekwondo training on oxidative stress and myokine levels in overweight and obese adolescents. Methods: We randomly assigned 20 overweight and obese adolescents to control (control group; CG, n = 10) and experimental (experimental group; EG, n = 10) groups. The EG performed Taekwondo training five times a week for 16 weeks. Physical parameters (height, weight, body mass index (BMI)), physical fitness (maximal oxygen uptake (VO 2 max) (cardiorespiratory endurance), grip and leg strength (muscular strength), sit-and-reach (flexibility), Sargent jump (power), and stork stand test (balance)) were measured before and after intervention. We measured levels of serum oxidative stress markers (plasma malondialdehyde (MDA) and superoxide dismutase (SOD)) and myokines (serum interleukin-15 (IL-15), brain-derived neurotrophic factor (BDNF), irisin, and myostatin). Results: The weight and BMI in the EG after intervention were significantly lower and leg strength (muscular strength), sit-and-reach (flexibility), and Sargent jump (power) were significantly improved compared to those of the CG (p < 0.05). There were no significant interaction effects in terms of height, VO 2 max, grip strength, or stork stand test (p > 0.05). The SOD and BDNF level after intervention were significantly higher in the EG after the intervention, whereas MDA and irisin levels were significantly lower than those of the CG (p < 0.05). There were no significant interaction effects in terms of serum IL-15 and myostatin levels (p > 0.05). Conclusions: Taekwondo training can reduce obesity and increase physical fitness with respect to muscular strength, flexibility, and power as well as alleviate oxidative stress and modulate myokine secretion in adolescents. pulmonary, cardiovascular, and musculoskeletal systems, inducing comorbidities such as type 2 diabetes mellitus, dyslipidemia, obstructive sleep apnea, and steatohepatitis [1]. Oxidative stress increased by obesity can exacerbate the severity of these diseases [5][6][7][8]. In particular, fat accumulation correlated with systemic oxidative stress, and increased fatty acids level increased oxidative stress through nicotinamide adenine dinucleotide phosphate (NADPH) oxidase activation [5,8]. Treatment with NADPH oxidase inhibitors decreased reactive oxygen species (ROS) production in adipose tissue and attenuated dysregulation of adipocytokines, improved diabetes, hyperlipidemia, and hepatic steatosis [5].A bout of high intensity exercise induces excessive ROS production that is linked with lipid and peroxidation, having deleterious impact on cells and tissues [9]. However, regular exercise with proper intensity is an effective way to prevent and improve obesity by increasing the activatio...

show abstract

“…Previous reports revealed that decrease in H2O2 by down regulation of superoxide dismutase activity supports apoptosis (Kahl et al, 2004). The enzymatic antioxidants of superoxide dismutases, catalases, glutathione system, thioredoxin system, peroxidase systems, flavo hemoglobins and nitrate or nitrite reductases play an important role in the scavenging of excess ROS and RNS species (Staerck et al, 2017).…”

Section: Discussionmentioning

confidence: 96%

Possible Association of Smokeless Tobacco Dependent Impairment in the Erythrocytes and Platelets Membranes of Human Male Volunteers: An Observation

Shaik

Nagajothi²,

Kodidela

et al. 2019

Asian Pac J Cancer Prev

View full text Add to dashboard Cite

Background:Smokeless tobacco (SLT) acts as a modifier of erythrocyte and platelet membranes by disrupting antioxidant system with the concomitant increase in free radical production and induction of apoptosis. Methods:The SLT users was that individuals used gutkha and khaini products (Khaleja/mahak chaini brand respectively) habitually, at least >20 times per week consists of 50-60 g during the last 2-4 years. Results:The gutkha and khaini users found to be significantly increased levels of iNOS (Inducible nitric oxide synthase) enzyme in plasma, erythrocytes, and platelet membranes when compared to normal controls. The gutkha and khaini users exhibited that the significant increase in the levels of gene expression of apoptotic proteins (Bcl2-B cell lymphoma gene 2, Bax, caspases 8, caspase 10, and caspase 12), IL-6 (Interleukin-6), and decreased levels of TNF-α (Tumor necrosis factor-alpha) and decreased expression of caspase 12 of khaini users were observed from blood samples. The significant increase in the concentrations of peroxynitrites (ONOO-), nitric oxide (NO) (Nitrates and nitrites), malondialdehyde (MDA), cholesterol, and phospholipids were reported in the smokeless tobacco users of erythrocytes and platelets. The experimental subjects showed that the increased osmotic fragility and decreased membrane fluidity of erythrocytes and platelets in comparison with non-tobacco users. The normal subjects had been exposed that the proper functioning of antioxidant enzymes and decreased enzyme activities of antioxidants were reported by SLT users. Conclusion:The smokeless tobacco products are exerted chronic damage to membranes of erythrocytes and platelets and elevation of apoptosis in the prolonged periods of human male volunteers.

show abstract

Microbial antioxidant defense enzymes

Cited by 202 publications

References 131 publications

Microbe‐Mediated Extracellular and Intracellular Mineralization: Environmental, Industrial, and Biotechnological Applications

Microbe‐Mediated Extracellular and Intracellular Mineralization: Environmental, Industrial, and Biotechnological Applications

Effects of Regular Taekwondo Intervention on Oxidative Stress Biomarkers and Myokines in Overweight and Obese Adolescents

Possible Association of Smokeless Tobacco Dependent Impairment in the Erythrocytes and Platelets Membranes of Human Male Volunteers: An Observation

Contact Info

Product

Resources

About