“…HPP stands on three basic principles: i) Le Chatelier's principle, which states that the application of pressure shifts the system equilibrium toward the state occupying the smallest volume and, thus, any phenomenon accompanied by a decrease in volume will be enhanced by an increase in pressure and vice versa; ii) Principle of microscopic ordering, which states that at constant temperature, an increase in pressure will increase the degrees of ordering of molecules of a given substance; and iii) Isostatic principle, which states that pressure is transmitted quasi-instantaneously and uniformly throughout the sample volume independently of the size and geometry of the product, this means that during HPP treatments all parts of the food will experience similar pressure, with pressure and temperature exerting antagonistic forces on molecular structure and chemical reactions (Balasubramaniam et al, 2008;Daryaei & Balasubramaniam, 2012;Yordanov & Angelova, 2014).…”