Microbial dysbiosis is evident in oral squamous cell carcinoma (OSCC) tissues of a group of Sri Lankan male patients with oral risk habits

Abstract

Our study identifies several potential periodontal pathogens, including Campylobacter concisus, Prevotella salivae, Prevotella loeschii, and Fusobacterium oral taxon 204. Additionally, Candida albicans is frequently associated with oral potentially malignant disorders (OPMDs) and oral cancers. Notably, we found a significant association between Candida etchellii and oral cancer for the first time. Furthermore, Capnocytophaga, Atopobium, and Candida were the most abundant microbial genera present in oral squamous cell carcinoma (OSCC) tissues.