Microbial effects (<i>Porphyromonas gingivalis, Tannerella forsythia</i>) after scaling and root planing

Octavia, Mora; Soeroso, Yuniarti; Kemal, Yulianti; Sunarto, Hari; Bachtiar, B. M.

doi:10.1088/1742-6596/1073/6/062011

Cited by 3 publications

(3 citation statements)

References 25 publications

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“…Moreover, the absolute difference of levels of microorganisms' bacterial load was also found during equiparation of healthy periodontal sites and healthy peri-implant regions, while statistically significant variations were noted considering bacterial load of P. gingivalis, T. forsythia and A. actinomycetemcomitans (p < 0, 05). Nevertheless, the results of our research should be interpreted with caution, since in another study of microbiota composition it was found that even though variations of species have been observed between affected and unaffected peri-implant/periodontal sites, such differences were smaller compared to inter subject differences (30). Analogical facts have been described in a number of previous studies, wherein individual oral microbiome composition and its associated changes were the most predominant factors of pathology development, and on which further treatment algorithms should be targeted (22, 25, and 26).…”

Section: Raspravamentioning

confidence: 52%

“…Štoviše, apsolutna razlika u razinama bakterijskog opterećenja također je utvrđena tijekom usporedbe zdravoga parodonta i zdravoga periimplantantnog područja, a zabilježene su statistički značajne varijacije kad se uzme u obzir bakterijsko opterećenje vrstama P. gingivalis, T. forsythia i A. actinomycetemcomitans (p < 0,05). Ali takve rezultate našeg istraživanja treba tumačiti s oprezom jer je u drugom istraživanju o sastavu mikrobioma utvrđeno da su, iako su primijećene varijacije vrsta između zahvaćenih i zdravih mjesta, takve razlike bile manje nego među subjektima (30). Analogne su činjenice opisane u mnogobrojnim dosadašnjim istraživanjima u kojima su individualni sastav oralnog mikrobioma i pridružene promjene bili dominantni čimbenici razvoja patologije i na koje trebaju biti usmjereni daljnji algoritmi liječenja (22,25,26).…”

Section: Raspravaunclassified

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Comparison of Bacterial Load Parameters in Subgingival Plaque during Peri-implantitis and Periodontitis Using the RT-PCR Method

Nastych

Goncharuk-Khomyn

Foros

et al. 2020

Acta Stomatol Croat

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Iako su parodontitis i periimplantitis uzročno povezani s takozvanim parodontopatogenim bakterijama, rezultati nedavno objavljenog sistematiziranog preglednog rada i metaanaliza dali su visokokvalitetne dokaze da obrazac bolesti određuju uglavnom kvantitativne karakteristike oralnoga mikrobioma, a ne samo određeni patogen (1, 2, 3, 4). Čini se da je mikrobiom kvalitativno razmjerno sličan u zdravom i bolesnom parodontu ili oko implantata, ali su uočene promje-ACTA STOMATOLOGICA CROATICA

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Section: Raspravamentioning

confidence: 52%

Section: Raspravaunclassified

Comparison of Bacterial Load Parameters in Subgingival Plaque during Peri-implantitis and Periodontitis Using the RT-PCR Method

Nastych

Goncharuk-Khomyn

Foros

et al. 2020

Acta Stomatol Croat

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“…The onset of periodontitis begins with microbial shifting from healthy oral microbes to being dominated by Gram-negative bacteria and obligate anaerobes. These two bacterial complexes that have an essential role in the development of periodontitis are red complex and orange complex bacteria, respectively, and are closely associated with periodontal PD [3,4].…”

Section: Introductionmentioning

confidence: 99%

Association between Volatile Sulfur Compounds Prevotella intermedia and Matrix Metalloproteinase-8 Expression

Maitimu

Soeroso

Sunarto

et al. 2022

Pesqui. Bras. Odontopediatria Clín. Integr.

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Objective: To determine the correlation between levels of methyl mercaptan (CH3SH) hydrogen sulfide (H2S), the proportion of Prevotella intermedia (Pi), and matrix metalloproteinase-8 (MMP-8) gene expression levels in periodontitis patients accompanied by halitosis. Material and Methods: Samples were obtained from gingival crevicular fluid (GCF) in the deepest pocket and by swabbing in the tongue coating area in patients with periodontitis presenting with halitosis (n = 23) and healthy subjects as controls (n = 7). The values of CH3SH and H2S were obtained using Oral Chroma. The proportion of Pi and MMP-8 expression levels were evaluated using PCR-RT. All the result was statistically analyzed using SPSS software. Results: The levels of CH3SH and H2S in participants with PD ≥ 6 mm showed a robust negative correlation with the proportion of P. intermedia in GCF and tongue coating. No statistically significant association was detected between CH3SH and H2S levels and MMP-8 expression levels (p>0.05). Conclusion:There is no association between CH3SH and H2S levels, the proportion of P. intermedia, and MMP-8 expression in patients with periodontitis accompanied by halitosis.

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Impact of nonsurgical and antibiotics treatment on periodontitis

Imran,

Al-Talib,

Malik

2023

MJBL

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Background: Periodontitis is one of the most prevalent chronic inflammatory noncommunicable and multifactorial diseases. Objectives: The present study was aimed to detect the effect of systemic antibiotics as disjunctive to nonsurgical treatment of generalized periodontitis (grade I and grade II) on the bacterial count and clinical periodontal parameters. Materials and Methods: Subgingival plaque samples were collected from 40 patients with generalized periodontitis, 20 patients were treated with scaling and root planning only, and 20 patients were treated with a combination of ciprofloxacin 500 mg and metronidazole 500 mg with scaling and root planning. Moreover, 20 samples were collected from healthy patients as a control group. Specific periodontal pathogen genes for Tannerella forsythia (BspA, CIpB genes) were identified using real time polymerase reaction (RT-PCR). Results: In this study, 120 samples were detected for the presence of T. forsythia by RT-PCR technique, and the specific ClpB, and BspA primers’ genes were used for the amplification of a fragment of these genes for the identification of T. forsythia. The results showed that the presence of ClpB and BspA in all (100%). BspA and ClpB showed a decrease but non-significant differences before and after treatment, whereas the periodontal parameter, probing pocket depth, plaque score, and bleeding on probing showed a significant decrease after treatment except clinical attachment lose showing a non-significant difference. Conclusion: Clinical treatment (scaling and root planning) is often helpful in the treatment of generalized periodontal disease (grade I and grade II) without the need for antimicrobial therapy as soon as possible.

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Microbial effects (Porphyromonas gingivalis, Tannerella forsythia) after scaling and root planing

Cited by 3 publications

References 25 publications

Comparison of Bacterial Load Parameters in Subgingival Plaque during Peri-implantitis and Periodontitis Using the RT-PCR Method

Comparison of Bacterial Load Parameters in Subgingival Plaque during Peri-implantitis and Periodontitis Using the RT-PCR Method

Association between Volatile Sulfur Compounds Prevotella intermedia and Matrix Metalloproteinase-8 Expression

Impact of nonsurgical and antibiotics treatment on periodontitis

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