Microbial Metabolites and Recent Advancement

Garia, Prakash; Chaubey, Kundan Kumar; Rawat, Harish; Sinha, Aashna; Sharma, Shweta; Goyal, Urvashi; Mittal, Amit

doi:10.1007/978-981-99-9037-5_14

Cited by 1 publication

(1 citation statement)

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“…Some plant-associated microbes produce bioactive metabolites that kill human pathogens and promote the growth of commensal bacteria (Kandasamy and Kathirvel, 2023 ). Omics-based screening can identify these microbial-derived compounds and reveal their mechanisms of action, enabling the development of new antimicrobials or probiotics for infectious diseases, inflammatory disorders, and metabolic syndromes (Garia et al, 2024 ). Plant-microbe interaction omics can also help personalize medicine by revealing inter-individual microbial community variability and dietary component interactions (Wright et al, 2023 ; Speckmann et al, 2024 ).…”

Section: Omics Advancement and Applicationsmentioning

confidence: 99%

Omics approaches in understanding the benefits of plant-microbe interactions

Jain,

Sarsaiya,

Singh

et al. 2024

Front. Microbiol.

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Plant-microbe interactions are pivotal for ecosystem dynamics and sustainable agriculture, and are influenced by various factors, such as host characteristics, environmental conditions, and human activities. Omics technologies, including genomics, transcriptomics, proteomics, and metabolomics, have revolutionized our understanding of these interactions. Genomics elucidates key genes, transcriptomics reveals gene expression dynamics, proteomics identifies essential proteins, and metabolomics profiles small molecules, thereby offering a holistic perspective. This review synthesizes diverse microbial-plant interactions, showcasing the application of omics in understanding mechanisms, such as nitrogen fixation, systemic resistance induction, mycorrhizal association, and pathogen-host interactions. Despite the challenges of data integration and ethical considerations, omics approaches promise advancements in precision intervention and resilient agricultural practices. Future research should address data integration challenges, enhance omics technology resolution, explore epigenomics, and understand plant-microbe dynamics under diverse conditions. In conclusion, omics technologies hold immense promise for optimizing agricultural strategies and fortifying resilient plant-microbe alliances, paving the way for sustainable agriculture and environmental stewardship.

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