Microbial production of carotenoids A review

Cardoso, Lígia Alves da Costa; Kanno, Karen Yuri Feitosa; Karp, Susan Grace

doi:10.5897/ajb2016.15763

Cited by 38 publications

(4 citation statements)

References 90 publications

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“…The main pigments synthesized by bacteria from the genus Mycolicibacterium (synonym Mycobacterium) are α-and β-carotene, lycopene, zeaxanthin, and astaxanthin [34][35][36][37]. Therefore, bacteria from this genus can be used as producers of these compounds.…”

Section: Discussionmentioning

confidence: 99%

“…The effect of temperature on the level of β-carotene biosynthesis in the mutant strain Ac-501/22 was studied by strain cultivation at four different temperatures (25,30,35, and 40 • C). The initial inoculate was grown at 30 • C, since this cultivation temperature was considered as the control [26,27].…”

Section: Effect Of Temperature On the Growth Of M Neoaurum Ac-501/22 ...mentioning

confidence: 99%

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Enhanced β-Carotene Production in Mycolicibacterium neoaurum Ac-501/22 by Combining Mutagenesis, Strain Selection, and Subsequent Fermentation Optimization

Yaderets,

Karpova,

Glagoleva

et al. 2023

Fermentation

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A continuing interest of scientists regarding the development of new β-carotene production technologies is due to the high biological activity of this compound and its wide application range. Bacteria are considered among the possible β-carotene producers convenient for industrial use. The purpose of this study was to develop a Mycolicibacterium neoaurum strain with an enhanced ability for β-carotene production and to optimize the fermentation conditions to improve the final yield of the target compound. Using chemical mutagenesis with N-nitroso-N-methylurea along with further strain selection, a M. neoaurum strain Ac-501/22, whose productivity was 2.7-fold higher than that of the parental strain Ac-501, was developed. The effect of nitrogen and carbon sources as well as cultivation conditions on the growth of M. neoaurum Ac-501/22 and β-carotene production were studied to select the optimal fermentation regime. Due to an increase in the temperature of cultivation from 30 to 35 °C, replacement of glucose with glycerin (20.0 g/L) and degreased soybean flour with powdered milk (10.0 g/L), and increase in the urea content from 0.5 to 1.0 g/L, the level of β-carotene production was improved to 183.0 mg/kg that was 35% higher than in the control. Further strain fermentation in a 3 L bioreactor using an optimized medium with the pH level maintained at 7.0–7.2 and 50% pO2 provided the maximum output of the target compound (262.4 mg/kg of dry biomass) that confirmed the prospects of the developed strain as an industrial β-carotene producer.

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Section: Discussionmentioning

confidence: 99%

Section: Effect Of Temperature On the Growth Of M Neoaurum Ac-501/22 ...mentioning

confidence: 99%

Enhanced β-Carotene Production in Mycolicibacterium neoaurum Ac-501/22 by Combining Mutagenesis, Strain Selection, and Subsequent Fermentation Optimization

Yaderets,

Karpova,

Glagoleva

et al. 2023

Fermentation

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“…β-karoten dünyada gıda renklendiricisi olarak margarin, peynir, meyve suları, süt ürünleri gibi ürünlerde sarı-turuncu renklerini vermek için en çok kullanılan pigmenttir [71]. β-karotenin gıdalarda renklendirici olması dışında A vitamini öncüsü ve yüksek antioksidan özelliğine sahip olması nedeniyle sağlık açısından da gıdaların fonksiyonel özelliklerini geliştirmektedir [73]. Astaksantin üretimi yapan alg Haematococus spp.…”

Section: Pigmentunclassified

Importance of Algae in Production of Sustainable Food, Food Supplements and Food Additives

KUMKAPU,

ŞAHİN YEŞİLÇUBUK

2023

Akademik Gıda

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Dünya nüfusunun hızla artması, çevresel bozulma, gıda kaynakları için rekabet ve tarımın uluslararası ekonomiye entegrasyonu gibi nedenler gıda sürdürülebilirliği için tehdit oluşturmaktadır. Günümüzde potansiyel yeni gıda kaynağı arayışı ön plandadır. Bu noktada algler öne çıkmaktadır. Algler içeriğinde protein, çoklu doymamış yağ asitleri, polisakkarit, pigment, sterol, vitamin ve mineraller gibi önemli biyoaktif bileşenler bulundurmaktadır. Bu değerli biyoaktif bileşenlere ek olarak alglerin doğal ve sürdürülebilir gıda kaynağı olarak görülmesinin nedenleri arasında alglerin bölünerek çoğalıp hızla biyokütle oluşturmaları ve uygun koşullarda açık sistemler kullanılarak düşük maliyetlerle yetiştirilebilmesi gibi faktörlerde bulunmaktadır. Alglerin gıda olarak tüketimi özellikle Uzak Doğu’da geleneksel bir uygulama olmasına rağmen, günümüzde alglerin gıda endüstrisinde ticarileşme potansiyeli, alglerin gıda katkısı, gıda takviyesi veya gıda bileşeni olarak kullanılmalarıyla artmaktadır. Tüm bu bilgiler doğrultusunda alglerin gıda endüstrisindeki öneminin yakın gelecekte artması beklenmektedir. Bu çalışmada biyoaktif bileşenler için potansiyel alg kaynakları, elde edilen ürünler ve günümüzdeki ticari üretimi konusunda bilgiler verilmiştir.

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“…Carotene is synthesized mainly by plants followed by other microorganisms like filamentous fungi, yeast, and bacteria which have been reported to display Pro-vitamin Activity and displays strong antioxidant activity. Carotene is used as food colorants, cosmetics, and in feed industries where their color ranges from yellow to red (Da Costa Cardoso et al, 2017). Carotene is a C40 Polyunsaturated hydrocarbon compound a resultant of condensation of C20 compounds (Liang et al, 2006).…”

Section: Carotenementioning

confidence: 99%

Marine Bacteria Is the Cell Factory to Produce Bioactive Pigments: A Prospective Pigment Source in the Ocean

Velmurugan

Venil

Ravi

et al. 2020

Front. Sustain. Food Syst.

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The course of investigations of bioactive compounds like bacterial pigments from the marine environment has greatly expanded in the recent decades. Despite the huge concern in secluding and collecting marine bacteria, microbial metabolites are progressively alluring to science due to their wide ranging applications in various fields, particularly those with distinctive color pigments. This review is a short appraisal of the studies undertaken over the past 5 years on the bacterial pigments sourced from the marine environment. Herein, we have reviewed the potential of different bacterial species isolated from marine environment in diverse studies that are producing bioactive pigments that have potential commercial applications.

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Microbial production of carotenoids A review

Cited by 38 publications

References 90 publications

Enhanced β-Carotene Production in Mycolicibacterium neoaurum Ac-501/22 by Combining Mutagenesis, Strain Selection, and Subsequent Fermentation Optimization

Enhanced β-Carotene Production in Mycolicibacterium neoaurum Ac-501/22 by Combining Mutagenesis, Strain Selection, and Subsequent Fermentation Optimization

Importance of Algae in Production of Sustainable Food, Food Supplements and Food Additives

Marine Bacteria Is the Cell Factory to Produce Bioactive Pigments: A Prospective Pigment Source in the Ocean

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