Microbiologic Findings in Patients with Chronic Suppurative Otitis Media

Nikakhlagh, Soheila; Khosravi, Azar Dokht; Fazlipour, A; Safarzadeh, Melody; Rashidi, Niloufar

doi:10.3923/jms.2008.503.506

Cited by 18 publications

(7 citation statements)

References 12 publications

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“…The results of the present study is similar to the findings of S. Nikakhlagh et al [28]. Aminu A. Bakari et al reported that most (95.5%) of the organisms were sensitive to ofloxacin; but isolates of P. aeruginosa and Klebsiella showed resistance to ofloxacin.…”

Section: Pattern Of Organismssupporting

confidence: 91%

Aerobic bacteriology of chronic suppurative otitis media and its antibiotic susceptibility pattern in a tertiary care hospital, Bagalkot

Gopal

Solabannavar

Riyas

2019

Trop J Pathol Microbiol

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Background: Chronic Suppurative Otitis Media (CSOM) remains one of the most common childhood chronic infectious diseases worldwide, affecting diverse racial and cultural groups both in developing and industrialized countries. India is one of the countries with highest CSOM prevalence (>6%) where urgent attention is needed. Infection usually results from bacterial, fungal and in some cases secondary to other viral infections like upper respiratory tract infections and tuberculosis. It is a common cause of conductive deafness which may lead to delayed development of speech and language in children and fatal intracranial complications. Change in the bacteriological scenario with indiscriminate use of antimicrobial agents has been associated with the emergence of multiple drug resistant strains. Therefore, the present study was carried out to determine the aerobic bacteria involved and their antibiotic susceptibility pattern in patients with CSOM. Methods: Ninety-three clinically diagnosed cases of CSOM of all age groups and both the sexes attending ENT OPD and admitted in ENT wards were studied. Two swabs were taken from each patient, one for Gram's staining and the other one for culture onto blood agar and MacConkey agar. After isolation, Gram stain, and biochemical reactions were done according to the procedures. Antibiotic susceptibility testing was done by Kirby-Bauer disc diffusion method. Results: 90.3% of the total samples yielded bacterial growth, while 9.68% were sterile. A total number of 10 different bacterial species were isolated from 89 isolates. The most common organism isolated was P.aeruginosa (30.3%) followed by S. aureus (27%), P. mirablilis (11.2%), K. pneumoniae (9%), E. coli (5.6%), CONS (5.6%), C. freundi (5.6%), Acinetobacter spp (2.2%), S. pyogenes (2.2%) and P.vulgaris (1.1%). Among Gram negative isolates the most sensitive drugs were amikacin and ofloxacin with 93.1% sensitivity, followed by piperacillin + tazobactam (88.9%) and ciprofloxacin (81%). Amoxyclav was the most resistant antibiotic (10.3%). The most effective antibiotic against gram positive bacteria in the present study was found to be ofloxacin and vancomycin (both 100% sensitivity), followed by chloramphenicol (96%). Ampicillin was the most resistant antibiotic, only 19.4% organisms were sensitive to it. Conclusion:The most common organism isolated was P.aeruginosa followed by S. aureus. The most effective antibiotic against gram positive bacteria was found to be ofloxacin. Among gram negative isolates the most sensitive drugs were amikacin and ofloxacin.

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Section: Pattern Of Organismssupporting

confidence: 91%

Aerobic bacteriology of chronic suppurative otitis media and its antibiotic susceptibility pattern in a tertiary care hospital, Bagalkot

Gopal

Solabannavar

Riyas

2019

Trop J Pathol Microbiol

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“…In the study by Nikakhlagh et al [14] in Iranian patients with CSOM reported that Staphylococcus aureus followed by Pseudomonas aeruginosa as the most isolated bacteria. In another study in Iran, Kalantar et al [15] isolated Staphylococci coagulase negative, Staphylococcus aureus and Streptococcus pneumonia in both the external ear canal of cancer patients and non-hospitalized cancer patients, similarly.…”

Section: Discussionmentioning

confidence: 98%

The Evaluation of Bacteremia, Bacterial Spectrum and Their Antibiotic Susceptibility Pattern in Chronic Otitis Media Patients Undergoing Tympanomastoidectomy

Jahangiri

Shishegar

2020

Egyptian Journal of Ear, Nose, Throat and Allied Sciences

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Background: Chronic otitis media (COM) endures be an important health problem across the world. Unleashed usage of antibiotics caused development of resistant bacterial strains for infections such as COM as well. Useful antibiotics therapy should be selected according to especially susceptibility pattern of most common local organisms. Aim: The study was conducted from July 2018 to June 2019 in one referral otolaryngology surgical center in the south of Iran to determine the causative microorganisms, their antibiotic sensitivity pattern and occurrence of bacteremia in chronic otitis media patients undergoing tympanomastoidectomy. Patients and Methods: This study designed with eighty-seven samples from eighty-seven ears which were obtained from patients who suffer from chronic otitis media. aerobic culturing and antibiotic sensitivity testing were done with standard antibiotic discs using the National Committee for Clinical Laboratory Standards guidelines. Also, venous blood samples were taken before and after the operation for microbiological study. fun Chi-square test, t-test were used for the statistical analysis in this study. Results: No microorganisms were isolated from the preoperative and post-operative blood cultures. Out of 87 patients, microbiological culture was yielded from 51 specimens (58.6 %). Staphylococci coagulase negative (n=19, 37%) was the most common isolate followed by Staphylococci coagulase positive (n=12, 23%). Susceptibility pattern of Staphylococci spp. showed that almost 80% isolates were sensitive to Ciprofloxacin followed by almost 60% to Co-trimoxazole. Conclusion:Our results proposed that bacteremia might not happen after tympanomastoidectomy. Continuous investigation of susceptibility pattern can improve the success of treatment process for chronic otitis media.

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“…Among 100 samples collected from 90 patients, 62 samples were bacterial culture positive with a culture positivity of 69%. In studies done by Vikas Khanna et al [3], V. K. Poorey et al [4], Tanmoy Dev et al [5], and S. Ni- kakhlagh et al [6] the culture positivity was 84%, 92%, 53% and 82% respectively. In our study all were monobacterial cultures where as in studies done by Vikas Khanna et al [3], V. K. Poorey et al [4] polymicrobial or mixed cultures were obtained in 39% and 10% respectively.…”

Section: Discussionmentioning

confidence: 99%

“…In study done by Vikas Khanna et al [3] the most common bacterial isolate was Pseudomonas aeruginosa (40.57%), followed by Staphylococcus aureus in 36.23% of cases. S. Nikakhlagh et al [6] studied that Staphylococcus aureus is common isolate in 32.4% followed by 21.69% of Pseudomonas aeruginosa. V. K. Poorey et al [4] observed that Pseudomonas pyocyaneous was the most common organism isolated in 35.2%, followed by Klebsiella aerogenes in 25.4%.…”

Section: Discussionmentioning

confidence: 99%

Clinical Application of a Microbiological Study on Chronic Suppurative Otitis Media

Moorthy¹,

Jadi²,

Katari³

et al. 2013

IJOHNS

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Our prospective study conducted over a period of 9 months includes 100 samples of ear discharge collected from 90 patients suffering from tubo-tympanic type of chronic suppurative otitis media (CSOM). The ear discharge which is collected with sterile swabs is subjected to Gram's staining and culture of the causative organism. Antibiotic sensitivity test of cultured bacterial growth is undertaken to know the susceptibility of the causative organism. Of the 100 samples, 62 were culture positive where Pseudomonas aeruginosa was the most common pathogen followed by Staphylococcus aureus. Most of the cultured organisms in our study were sensitive to drug Ciprofloxacin. The outcome of our study enabled us to set an empirical medical treatment for an early resolution of ear discharge and inflammation in our patients with CSOM as we could understand the aetiological pathogens and their susceptibility pattern. Effective medical treatment in obtaining a discharge free ear prior to surgical treatment led us to improve the surgical outcome in our patients with CSOM.

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Microbiologic Findings in Patients with Chronic Suppurative Otitis Media

Cited by 18 publications

References 12 publications

Aerobic bacteriology of chronic suppurative otitis media and its antibiotic susceptibility pattern in a tertiary care hospital, Bagalkot

Aerobic bacteriology of chronic suppurative otitis media and its antibiotic susceptibility pattern in a tertiary care hospital, Bagalkot

The Evaluation of Bacteremia, Bacterial Spectrum and Their Antibiotic Susceptibility Pattern in Chronic Otitis Media Patients Undergoing Tympanomastoidectomy

Clinical Application of a Microbiological Study on Chronic Suppurative Otitis Media

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