Early stage of the disease looks like abscess and cellulitis. This benign image is the most important reason behind late diagnosis. But, cellulitis can be a very dangerous disease because of its tendency to spread the infection through blood or lymph and deeper pe-ABSTRACT Deep neck infections still remain one of the important causes of morbidity, although their prevalence has been diminished with modern antimicrobal therapy. The target of the retrospective is to demonstrate our experience in the treatment of serious cases of deep neck infections (phlegmons) and to identify the predictors of a possibly poor outcome. This retrospective study comprised 44 patients with neck phlegmons, who were treated at the ENT Clinic, during 2000-2016. The study included the etiology, predisposing factors, causative microbiological organisms, and the clinical outcomes associated with the mortality. During investigated time period, 44 patients with deep neck infections (phlegmons) were noted. The median age of the patients was 45.9 years (range, 14-81), and study population included 26 males (59%). The median hospital stay was 22.5 days (from 3-80 days). Staphylococcus aureus was the most commonly isolated bacteria. Death was noted in 10 patients (22.7%). Timely diagnosis together with aggresive surgical treatment and appropriate antibacterial therapy were the key to sucess in the treatment of the patients with deep neck infections. The factors associated with poor prognosis in our patients included tonsillar disease, diabetes mellitus, mediastinitis, age above 65 years.