Microbiological and Epidemiological Features of Mycobacteriosis

Petrov, Ivo; Амирова, Т. Х.; Петрова, Л. В.; Petrova, Firuza Salavatovna; Севастьянова, Е.В.; Валиев, Р И

doi:10.31631/2073-3046-2020-19-3-89-94

Cited by 5 publications

(2 citation statements)

References 22 publications

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“…Thus, in the clinical picture of the combination NTMPD and pTB, there are no pathognomonic clinical and radiographic symptoms, which is noted by most authors [2][3][4][5]. However, the presence of an indolent course, hemoptysis and bronchiectasis in the presence of MBT in the sputum makes it possible to suspect a combination of NTMPD and pTB, which requires in-depth bacteriological examination and, additionally, more careful reexamination for radiographic and clinical signs.…”

Section: Discussionmentioning

confidence: 99%

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A Comparison of Clinical and Radiographic Signs of Nontuberculous Mycobacterial Pulmonary Disease, Destructive Drug-Resistant Pulmonary Tuberculosis and a Combination of Nontuberculous Mycobacterium Pulmonary Disease and Pulmonary Tuberculosis

Giller,

Scherbakova,

Enilenis

et al. 2023

Pathogens

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A misdiagnosis of isolated pulmonary tuberculosis (pTB) is highly likely when a patient has nontuberculous mycobacterial pulmonary disease (NTMPD) or a combination of nontuberculous mycobacterium pulmonary disease and pulmonary tuberculosis. Frequently, bacterial excretion is absent or only Mycobacteria tuberculosis (MBT) is found. This often results in an incorrect diagnosis and subsequent misinformed treatment regimes. In order to determine possible clinical and radiographic differences between patients with NTMPD (Group 1), destructive drug-resistant pulmonary tuberculosis (Group 3) and a combination of NTMPD and pTB (Group 2) we compare clinical and radiographic signs for these three patient groups. When comparing with Group 3 (2.5%), Groups 1 (25%) and 2 (17.4%) have a substantially higher incidence of pulmonary haemorrhages. Thus, upon clinically observing the combination of pTB and NTMPD, there are no pathognomonic clinical and radiographic detected symptoms. However, the presence of an indolent course, hemoptysis and bronchiectasis in the presence of acid-fast bacteria (or identified MBT) in the sputum makes it possible to suspect not simple pTB, but a combination of pTB and NTMPD. To clarify this necessitated in-depth bacteriological examination.

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Section: Discussionmentioning

confidence: 99%

“…Furthermore, NTM are conditionally pathogenic. Consequently, a single isolation of these bacteria from the respiratory tract only indicates body media colonisation and does not unequivocally define the presence of disease [ 1 , 2 , 3 , 4 , 5 , 6 , 7 ].…”

Section: Introductionmentioning

confidence: 99%

A Comparison of Clinical and Radiographic Signs of Nontuberculous Mycobacterial Pulmonary Disease, Destructive Drug-Resistant Pulmonary Tuberculosis and a Combination of Nontuberculous Mycobacterium Pulmonary Disease and Pulmonary Tuberculosis

Giller,

Scherbakova,

Enilenis

et al. 2023

Pathogens

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Prospects of Using Pharmacologically Active Compounds for the Creation of Antimycobacterial Drugs

et al. 2022

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Mycobacterial infections: features of microbiological diagnosis

Lutsenko,

Yasenyavskaya,

Samotrueva

2024

Sibirskij nauchnyj medicinskij zhurnal

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To date, more than 200 species of mycobacteria have been identified, in addition to the well-known Mycobacterium leprae and Mycobacterium tuberculosis. Among microorganisms belonging to the genus Mycobacterium, there are obligate pathogenic, opportunistic and saprophytic strains. The incidence of non-tuberculous or atypical mycobacteria, which cause opportunistic infections in humans and animals, is steadily increasing. Non-tuberculous mycobacteria are increasingly recognized as a source of healthcare-associated infections.Aim of the study was to analyze the literature on current methods of microbiological diagnosis of mycobacterial infections.Material and methods. A search and analysis of scientific literature in the Web of Science, PubMed, eLIBRARY.RU, Europe PMC databases was performed using the following key words: mycobacteriosis, non-tuberculous mycobacteria, mycobacterial infections, MALDITOF MS, atypical mycobacteria. Results and discussion. The review summarizes and presents the classification, morphological, cultural, genetic and ecological features of mycobacterial strains. Modern approaches in the diagnosis of mycobacterial diseases and identification of pathogens are analyzed; their advantages and disadvantages are indicated.Conclusions. Mycobacterial infections are often considered as diseases associated with the provision of medical care, requiring a detailed assessment of the situation with the definition of criteria for microbiological monitoring of objects of a medical organization, etc. The analyzed literature data demonstrate a variety of methods for laboratory diagnosis of mycobacterial infections with the need for further improvement of methodological approaches.

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Microbiological and Epidemiological Features of Mycobacteriosis

Cited by 5 publications

References 22 publications

A Comparison of Clinical and Radiographic Signs of Nontuberculous Mycobacterial Pulmonary Disease, Destructive Drug-Resistant Pulmonary Tuberculosis and a Combination of Nontuberculous Mycobacterium Pulmonary Disease and Pulmonary Tuberculosis

A Comparison of Clinical and Radiographic Signs of Nontuberculous Mycobacterial Pulmonary Disease, Destructive Drug-Resistant Pulmonary Tuberculosis and a Combination of Nontuberculous Mycobacterium Pulmonary Disease and Pulmonary Tuberculosis

Prospects of Using Pharmacologically Active Compounds for the Creation of Antimycobacterial Drugs

Mycobacterial infections: features of microbiological diagnosis

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