Microbiological characteristics of perianal streptococcal dermatitis: a retrospective study of 105 patients in a 10-year period

Šterbenc, Anja; Seme, Katja; Lah, Liza Lea; Točkova, Olga; Trop, Tina Kamhi; Švent-Kučina, Nataša; Pirš, Mateja

doi:10.15570/actaapa.2016.21

Cited by 3 publications

(15 citation statements)

References 20 publications

(67 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This is in contrast to PSD in children, in which group A β-haemolysing Streptococci (GABHS) are predominant. This difference in groups of BHS in association with age also was observed by Sterbenc et al [3]. While children with PSD can be cured in almost all cases by eradication of Streptococci with systemic antibiotic treatment, we demonstrated that in adults, a substantial percentage of patients require continuing or further treatment of their concomitant anorectal disease in addition to treatment of PSD to achieve freedom from symptoms.…”

supporting

confidence: 88%

“…In contrast to children, in whom PSD was mostly caused by GABHS, adult PSD was associated with GBBHS. This finding was confirmed by Sterbenc et al [3]. In paediatric PSD patients, eradication by systemic antibiotics lead to an almost 100% cure rate.…”

Section: Discussionsupporting

confidence: 54%

“…In both cohorts, GBBHS was the cause of PSD in the majority of cases. GGBHS was cultured second most frequently and has also been described in other reports on adult PSD [3,12,14,15].…”

Section: Discussionmentioning

confidence: 69%

“…The clinical pattern is mainly defined by clearly marked perianal erythema. Itching, burning and soiling are typically reported [2][3][4][5][6][7][8][9][10]. The erythema can be associated with induration and even pain.…”

Section: Discussionmentioning

confidence: 99%

“…While children with PSD can be cured in almost all cases by eradication of Streptococci with systemic antibiotic treatment, we demonstrated that in adults, a substantial percentage of patients require continuing or further treatment of their concomitant anorectal disease in addition to treatment of PSD to achieve freedom from symptoms. Although topical antibiotic therapy with, e. g., erythromycin or mupirocin has been advocated for paediatric PSD by some authors in the past [3][4][5], most dermatologists and paediatrics will treat PSD by oral antibiotics.…”

mentioning

confidence: 99%

See 4 more Smart Citations

Perianal streptococcal dermatitis in adults

Kahlke

Feeser²,

Jongen³

et al. 2018

coloproctology

View full text Add to dashboard Cite

show abstract

supporting

confidence: 88%

Section: Discussionsupporting

confidence: 54%

“…In both cohorts, GBBHS was the cause of PSD in the majority of cases. GGBHS was cultured second most frequently and has also been described in other reports on adult PSD [3,12,14,15].…”

Section: Discussionmentioning

confidence: 69%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

See 3 more Smart Citations

Perianal streptococcal dermatitis in adults

Kahlke

Feeser²,

Jongen³

et al. 2018

coloproctology

View full text Add to dashboard Cite

show abstract

Perianal streptococcal disease in childhood: systematic literature review

et al. 2021

View full text Add to dashboard Cite

Group A Streptococcus has been associated with a perianal infection. We conducted a systematic review of the literature on childhood streptococcal perianitis in three databases: Excerpta Medica, National Library of Medicine, and Web of Science. The main purposes were to document the clinical features, the tendency to recur, the association with an asymptomatic streptococcal throat carriage, the accuracy of rapid streptococcal tests, and the mechanism possibly underlying the acquisition of this infection. More than 80% of cases are boys ≤7.0 years of age with defecation disorders, perianal pain, local itch, rectal bleeding, or fissure and a sharply demarcated perianal redness. Perianitis is associated with a streptococcal tonsillopharyngitis in about every fifth case. The time to diagnosis is ≥3 weeks in 65% of cases. Recurrences occur within 3½ months in about 20% of cases. An asymptomatic group A streptococcal throat carriage occurs in 63% of cases. As compared with perianal Streptococcus A culture, the rapid streptococcal tests have a positive predictive value of 80% and a negative predictive value of 96%. It is hypothesized that digital inoculation from nasopharynx to anus underlies perianitis. Many cases are likely caused directly by children, who are throat and nasal carriers of Streptococcus A. Some cases might occur in children, who have their bottoms wiped by caregivers with streptococcal tonsillopharyngitis or carriage of Streptococcus.Conclusion: Perianitis is an infection with a distinctive presentation and a rather long time to diagnosis. There is a need for a wider awareness of this condition among healthcare professionals. What is Known:• Group A Streptococcus may cause perianitis in childhood.• Systemic antimicrobials (penicillin V, amoxycillin, or cefuroxime) are superior to topical treatment. What is New:• The clinical presentation is distinctive (defecation disorders, perianal pain, local itch, rectal bleeding, or fissure and a sharply demarcated perianal redness).• The time to diagnosis is usually ≥3 weeks.Recurrences occur in about 20% of cases.

show abstract

Perianal infectious dermatitis: An underdiagnosed, unremitting and stubborn condition

Serban

2018

WJCP

View full text Add to dashboard Cite

Perianal infectious dermatitis (PID) represents a superficial inflammation of the perianal skin, which is of bacterial origin (classically, group A beta-hemolytic streptococci). This narrative review aims to critically review and summarize the available scientific literature regarding pediatric PID, being the first of its kind, to the best of the author’s knowledge. It also reports the first cases of Romanian children with PID. Multiple databases were subjected to systematic literature search (from 1966 to April 30, 2018) to identify studies and case reports of children with PID. As such, this review provides updated information about essential aspects of PID (epidemiology, etiology, pathogenesis, as well as clinical features, required investigations and therapeutic options) and of diagnostic pitfalls. Although a well-defined entity, PID remains largely underdiagnosed. PID may mimic other common conditions with skin manifestations (like candidiasis, pinworms, eczema, irritant dermatitis, anal fissure, hemorrhoids, Crohn’s disease, psoriasis, seborrheic dermatitis, zinc deficiency dermatosis and even sexual abuse), with consequent unnecessary, sometimes expensive and invasive investigations and futile therapies, which cause patients and families discomfort and distress. Since PID has an unremitting course, early recognition is imperative, as it allows for prompt and efficacious antibiotic therapy. However, PID represents a stubborn condition and, even if properly treated, its recurrence rate remains high. Further well-designed prospective randomized controlled trials, with adequate follow-up, are required in order to formulate the optimum personalized antibiotic therapy (oral alone or in association with topical medication), able to prevent recurrences. Awareness of this condition by healthcare professionals should improve patient outcomes.

show abstract

Microbiological characteristics of perianal streptococcal dermatitis: a retrospective study of 105 patients in a 10-year period

Cited by 3 publications

References 20 publications

Perianal streptococcal dermatitis in adults

Perianal streptococcal dermatitis in adults

Perianal streptococcal disease in childhood: systematic literature review

Perianal infectious dermatitis: An underdiagnosed, unremitting and stubborn condition

Contact Info

Product

Resources

About