Microbiological characterization of severe exacerbations in Chronic Obstructive Pulmonary Disease (COPD) in patients admitted to the ICU with or without associated pneumonia: A retrospective cross-sectional study

Varón, Fabio Andrés; Torres-Caro, Cristina; Herrera-Diaz, Catalina; Ali, Abraham; Hernández-Parra, Ángela; Aguirre-Franco, Carlos; Uribe-Hernández, Ana María

doi:10.22354/in.v23i4.803

Cited by 3 publications

(1 citation statement)

References 17 publications

(14 reference statements)

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“…In Colombia, the expert presented that M. catarrhalis and H. influenzae are the main bacterial isolates from patients with severe COPD exacerbations. 29 Although these data cannot be extrapolated for non-intensive care unit (ICU) patients, they are an indication of the distribution of the bacterial etiology of AE-COPD for hospitalized patients: H. influenzae 25%, M. catarrhalis 25%, H. parainfluenzae:15%, Pseudomonas spp. 6%, and S. pneumoniae 7%.…”

Section: Etiology Datamentioning

confidence: 99%

<p>Highlights of an Expert Advisory Board on Acute Exacerbations of Chronic Obstructive Pulmonary Disease (AE-COPD) in Latin America</p>

Naranjo

Torres-Duque

Colodenco

et al. 2020

COPD

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Background Chronic obstructive pulmonary disease (COPD) is a preventable and usually progressive lung disease that affects millions of people worldwide and is the sixth leading cause of death in the Americas. Viral and bacterial respiratory tract infections and air pollution may cause acute exacerbations of COPD (AE-COPD) ranging from mild, moderate to severe. The greatest proportion of the overall COPD burden on the health system is due to disease exacerbations. There is limited evidence regarding the etiology and burden of AE-COPD in Latin America (LATAM). Methods To respond to this gap in evidence, an Advisory Board with regional pneumologists and infectious disease experts was convened in September 2018 in Panama City, Panama, to: 1) review the burden of AE-COPD in LATAM; 2) evaluate the etiology of AE-COPD in LATAM; and 3) assess and compare the local/regional guidelines to confirm the etiology, characterize, and manage AE-COPD. Results The results of the meeting showed that there is a high prevalence of AE-COPD in LATAM countries, limited evidence on etiology data, and discrepancies in the case definitions and symptomology (ie, severity) classifications used in LATAM. Conclusion The Advisory Board discussions further resulted in recommendations for future research on the impact on the epidemiology and burden of disease, on establishing standardized AE-COPD case definition guidelines, and on studying the etiology of both moderate and severe AE-COPD cases.

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Section: Etiology Datamentioning

confidence: 99%

<p>Highlights of an Expert Advisory Board on Acute Exacerbations of Chronic Obstructive Pulmonary Disease (AE-COPD) in Latin America</p>

Naranjo

Torres-Duque

Colodenco

et al. 2020

COPD

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Prevalence, Pattern, Risks Factors and Consequences of Antibiotic Resistance in COPD: A Systematic Review

Smith

Gill

Hall

et al. 2021

COPD: Journal of Chronic Obstructive Pulmonary Disease

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C-reactive Protein (CRP) as Diagnostic Marker of Pneumonia in Children

Naz

2021

ASMScJ

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Pneumonia is an inflammation of the lung parenchyma tissue that mainly affects the respiratory bronchioles and alveoli. The present research study is focused on assessment of the C-reactive protein (CRP) test as a tool marker for the diagnosis of pneumonia among children. In the current study, a total of 450 patients admitted to the children ward at Lady Reading Hospital (LRH) Peshawar, Khyber Pakhtunkhwa, Pakistan were selected, out of which 55% were male and 45% were female. In addition, two groups were designed according to age i.e. 1-8 years and 9-16 years of age with a frequency of 55 and 45%, respectively. In case of chest X-ray assessment, it was observed that all patients were highly susceptible to pneumonia infection, while from blood culture analysis, it was perceived that 419 patients (93%) were highly susceptible to pneumonia infection. Two bacterial isolates (Klebsiella pneumoniae and Streptococcus pneumoniae) were characterised from all positive samples. In contrast with CRP assessment, 385 patients (85%) had positive CRP reports displaying more than 5 mg/L CRP values and 65 patients (15%) had negative CRP reports. Thus, it was concluded that patients with high CRP values presented clear evidence of a severe infection. Moreover, it is suggested that CRP is a sensitive, less time consuming and inexpensive technique; therefore, it has been recommended to be used as a tool marker along with other diagnostic techniques for the diagnosis of life-threaten infections to get a more clear picture about infections.

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Microbiological characterization of severe exacerbations in Chronic Obstructive Pulmonary Disease (COPD) in patients admitted to the ICU with or without associated pneumonia: A retrospective cross-sectional study

Cited by 3 publications

References 17 publications

<p>Highlights of an Expert Advisory Board on Acute Exacerbations of Chronic Obstructive Pulmonary Disease (AE-COPD) in Latin America</p>

<p>Highlights of an Expert Advisory Board on Acute Exacerbations of Chronic Obstructive Pulmonary Disease (AE-COPD) in Latin America</p>

Prevalence, Pattern, Risks Factors and Consequences of Antibiotic Resistance in COPD: A Systematic Review

C-reactive Protein (CRP) as Diagnostic Marker of Pneumonia in Children

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