Microbiological Quality in Cosmetics

March, Gabriel A.; Garcia-Loygorri, Maria C.; Eiros, Jose M.; Bratos, Miguel Ángel; Lejarazu, Raúl Ortíz de

doi:10.1016/b978-0-444-63508-2.00018-7

Cited by 3 publications

(3 citation statements)

References 34 publications

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“…Although preservatives are added to cosmetic formulations to avoid bacterial contamination, these products are recognized to be suitable substrates for the growth and survival of a large variety of microorganisms, since they posse some of the nutrients that facilitate growth, such as water, lipids, polysaccharides, alcohols, proteins, amino acids, glycosides, peptides, and vitamins [5,6]. Besides, inadequate storage conditions, such as high temperature and/or humidity exposition, and the use of expired products (the lifetime of the product is limited by the protection afforded by the preservation), can favor undesired microbial growth in the formulations.…”

Section: Figurementioning

confidence: 99%

“…This study also evaluated the CFU of beauty blenders, employed to homogenize the cosmetics, especially on the face. These products showed a worrying level higher than 10 6 CFU per g. Most of the employed techniques for detecting bacteria in cosmetics, including the official methodology, are based on the CFU count [4, 6,10] and although they employ low-cost materials, they are laborious and require several steps, being very time consuming (up to 72 h). In addition, due to the broad variety of cosmetics available in the current market, including some 'extreme formats' and borderline products [11], such control methods are often not suitable for several types of products, like water-immiscible cosmetics.…”

Section: Figurementioning

confidence: 99%

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Tracking Bacterial Spoilage in Cosmetics by a New Bioanalytical Approach: API-SPME-GC-MS to Monitor MVOCs

Celeiro

Varela²,

Rodríguez³

et al. 2020

Cosmetics

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The main goal of this work was the use of the powerful solid-phase microextraction-gas chromatography-mass spectrometry (SPME-GC-MS) technique to unequivocally identify microbial volatile organic compounds (MVOCs) derived from the enzymatic activity produced during metabolic processes using analytical profile index (API) biochemical tests. Three bacteria were selected for this study: Escherichia coli, Proteus mirabilis, and Pseudomonas aeruginosa. They were inoculated and incubated to both API components and real cosmetics, as well as to a mixture of them. Specific MVOCs were successfully identified as biomarkers for each one of the studied microorganisms: Indole and 2-nitrophenol as Escherichia coli markers, 2-undecanone and phenylethyl alcohol as Proteus mirabilis-specific markers, and 1-undecene and 2′-aminoacetophenone as Pseudomonas aeruginosa ones. In addition, a high number of MVOCs were identified as general markers of bacterial presence. The results revealed that the MVOCs’ formation is highly subtract dependent. Therefore, the ultimate and most challenging objective is to establish a relationship between the identified MVOCs and the original compound present in the substrate. This work establishes the design and development of this original approach, and its practical application to the control of microbial contamination in real cosmetic samples.

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Section: Figurementioning

confidence: 99%

Section: Figurementioning

confidence: 99%

Tracking Bacterial Spoilage in Cosmetics by a New Bioanalytical Approach: API-SPME-GC-MS to Monitor MVOCs

Celeiro

Varela²,

Rodríguez³

et al. 2020

Cosmetics

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“…Therefore, every manufacturer of cosmetics has a responsibility to ensure the microbiological safety of its products for the intended use lifespan [ 28 ]. Under EU cosmetics regulations, each cosmetic product placed on the market should have its own Product Information File (PIF) which captures details on the microbiological quality of the raw materials and the finished product [ 29 ].…”

Section: Introductionmentioning

confidence: 99%

In-vivo impact of common cosmetic preservative systems in full formulation on the skin microbiome

et al. 2021

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Preservatives play an essentially role in ensuring that cosmetic formulations remain safe for use via control of microbial contamination. Commonly used preservatives include organic acids, alcohols and phenols and these play an essential role in controlling the growth of bacteria, fungi and moulds in substrates that can potentially act as a rich food source for microbial contaminants. Whilst the activity of these compounds is clear, both in vitro and in formulation, little information exists on the potential impact that common preservative systems, in full formulation, have on the skin’s resident microbiome. Dysbiosis of the skin’s microbiome has been associated with a number of cosmetic conditions but there currently are no in vivo studies investigating the potential for preservative ingredients, when included in personal care formulations under normal use conditions, to impact the cutaneous microbiome. Here we present an analysis of four in vivo studies that examine the impact of different preservation systems in full formulation, in different products formats, with varying durations of application. This work demonstrates that despite the antimicrobial efficacy of the preservatives in vitro, the skin microbiome is not impacted by preservative containing products in vivo.

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Isolation of valuable substances from berry seeds and pomace by the green high-pressure methods, their evaluation and application in cosmetic creams

Grabauskaitė,

Jūrienė,

Pukalskienė

et al. 2024

Industrial Crops and Products

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Microbiological Quality in Cosmetics

Cited by 3 publications

References 34 publications

Tracking Bacterial Spoilage in Cosmetics by a New Bioanalytical Approach: API-SPME-GC-MS to Monitor MVOCs

Tracking Bacterial Spoilage in Cosmetics by a New Bioanalytical Approach: API-SPME-GC-MS to Monitor MVOCs

In-vivo impact of common cosmetic preservative systems in full formulation on the skin microbiome

Isolation of valuable substances from berry seeds and pomace by the green high-pressure methods, their evaluation and application in cosmetic creams

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