Microbiology and management of brain abscess in children

Brook, Itzhak

doi:10.1055/s-0035-1557207

Cited by 5 publications

(1 citation statement)

References 19 publications

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“…The pathophysiology of the appearance of brain abscesses (as well as subdural and extradural empyema) in the pediatric population is various. They are the outcome of [ 31 ]: Direct expansion of intracranial growth (or infection of contiguous structures) associated with otitis, sinusitis, as well as untreated dental diseases. Contiguous spread, which leads to the emergence of retrograde meningitis, cavernous sinus thrombosis, and epidural, subdural, and brain abscess.…”

Section: Discussionmentioning

confidence: 99%

COVID-19 Co-Infection May Promote Development of Sinusitis Complication in Children

Szewczyk

Mitosek-Szewczyk

2022

Children

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Background: The olfactory dysfunction that occurs during a COVID-19 infection has sparked much debate about its similarity to sinusitis. Up to 65% of COVID-19 pediatric patients may be asymptomatic; however, when symptoms are observed, fever and cough are the most common. Nasal congestion and discharge as well as headaches can also be seen, which makes both entities, i.e., COVID-19 and sinusitis, similar to each other. Methods: In this review, we present the clinical case of a teenager with a history of acute sinusitis and COVID-19 co-infection followed by purulent meningoencephalitis. We aim to summarize available findings on the association between COVID-19, sinusitis, and possible common complications of both diseases. Results: Differentiating between COVID-19 and sinusitis can be confusing because presented symptoms may overlap or mimic each other. Increased risk of complications, especially in patients with bacterial sinusitis co-infected with SARS-CoV-2, should prompt physicians to monitor young patients and inform parents about disturbing symptoms and possible complications. Conclusions: Acute sinusitis and COVID-19 co-infection may lead to numerous complications and should be included among the factors predisposing to worse prognosis. It is especially related to patients with high risk factors and even more important in children as they often pass the infection asymptomatically and its complications can lead to loss of health or life.

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Section: Discussionmentioning

confidence: 99%

COVID-19 Co-Infection May Promote Development of Sinusitis Complication in Children

Szewczyk

Mitosek-Szewczyk

2022

Children

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Microbiology of Intracranial Abscesses and Their Associated Sinusitis

Brook¹

2005

Arch Otolaryngol Head Neck Surg

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To evaluate the organisms recovered from infected sinuses and associated intracranial abscesses (IAs). Design: Retrospective review of findings from aspirate of pus from 10 infected sinuses and their corresponding IAs. Setting: Academic medical center. Patients: Ten patients diagnosed as having sinusitis (age range, 7-58 years). Main Outcome Measure: Aerobic and anaerobic bacteria findings from infected sinuses and IAs. Results: Polymicrobial flora was found in 9 sinuses and 8 IAs. Anaerobes were isolated from all sinuses and 9 IAs. A total of 26 isolates (2.6 isolates per specimen) were recovered from the sinuses: 19 anaerobic, 6 aerobic or facultative, and 1 microaerophilic; 17 isolates were found in the IAs (1.7 isolates per site): 13 anaerobic, 2 aerobic or facultative, and 2 microaerophilic. The predominant anaerobes were Fusobacterium species (in 5 corresponding sinuses and abscesses, 1 in a sinus only, and 1 in an IA only), Prevotella species (in 3 corresponding sinuses and abscesses), Peptostreptococcus species (in 2 corresponding sinuses and abscesses, and 4 in a sinus only), Staphylococcus aureus, Haemophilus influenzae type b, microaerophilic streptococci, and Bacteroides ureolyticus (in 1 corresponding sinus and abscess each). Streptococcus pneumoniae was recovered 2 times, only from a sinus. ␣-Hemolytic streptococci and ␤-hemolytic streptococci group F were each isolated once from the sinus. Concordance in the microbiological findings between the sinus and the IA was found in all instances. However, certain organisms were present at only one or the other site. Conclusion: These data illustrate the concordance in the recovery of organisms from infected sinuses and their associated IA and confirm the importance of anaerobic bacteria in sinusitis and IA.

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Bacteroides and Prevotella Species and Other Anaerobic Gram–Negative Bacilli

Brook¹

2008

Principles and Practice of Pediatric Infectious Disease

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Microbiology and management of brain abscess in children

Cited by 5 publications

References 19 publications

COVID-19 Co-Infection May Promote Development of Sinusitis Complication in Children

COVID-19 Co-Infection May Promote Development of Sinusitis Complication in Children

Microbiology of Intracranial Abscesses and Their Associated Sinusitis

Bacteroides and Prevotella Species and Other Anaerobic Gram–Negative Bacilli

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