Microbiology of skin and soft tissue infections in the age of community-acquired methicillin-resistant Staphylococcus aureus

Ray, G. Thomas; Suaya, José A.; Baxter, Roger

doi:10.1016/j.diagmicrobio.2013.02.020

Cited by 84 publications

(59 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Another study of pediatric inpatients in California noted a rapid rise in MRSA hospitalizations between 2002 and 2006, followed by a subsequent decrease in MRSA hospitalizations; MSSA hospitalizations remained at relatively stable rates. 23,24 These shifts are similar to the trends in proportion of MRSA we identified in our pediatric population. Pediatric patients defi ned as being <18 y of age and are not active duty.…”

Section: Discussionsupporting

confidence: 72%

“…1-4, 12, 26, 27 A parallel decline in MSSA infections has not been consistently reported, with some authors noting stable rates of MSSA during the same time period. 24,27 Landrum et al 3 reported a significant decline in the rate of bacteremia, but not SSTIs, due to both MRSA and MSSA between 2005 and 2010. However, the proportion of MRSA among S aureus community-onset SSTIs did significantly decrease.…”

Section: Discussionmentioning

confidence: 99%

“…3,4,6,23 Before 2005, dramatic increases in rates of community-associated MRSA infection were reported, with most studies revealing oxacillin resistance in 40% to 60% of SSTIs. 16,24,25 The rate of rise of MRSA infections slowed by 2005-2006 and subsequently declined. 1-4, 12, 26, 27 A parallel decline in MSSA infections has not been consistently reported, with some authors noting stable rates of MSSA during the same time period.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Changing Susceptibility of Staphylococcus aureus in a US Pediatric Population

et al. 2016

View full text Add to dashboard Cite

show abstract

Section: Discussionsupporting

confidence: 72%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Changing Susceptibility of Staphylococcus aureus in a US Pediatric Population

et al. 2016

View full text Add to dashboard Cite

show abstract

“…6,28 In a 10-year study (1998)(1999)(2000)(2001)(2002)(2003)(2004)(2005)(2006)(2007), abscess and wound isolates caused by MRSA increased nearly 8-fold (70.4%) and 4-fold (55.2%), respectively. 29 Ray et al 30 reported that the rate of MRSA stabilized or decreased slightly between 2005 and 2009; however, 80% of culture-positive skin infections were caused by S aureus, and half were due to MRSA. Findings of the Sentry Antimicrobial Monitoring program provide some insight into the occurrence rate of less common pathogens isolated from SSTIs during a 7-year period (1998)(1999)(2000)(2001)(2002)(2003)(2004).…”

Section: Imagingmentioning

confidence: 99%

Hospitalist Perspective on the Treatment of Skin and Soft Tissue Infections

Amin

Cerceo

Deitelzweig

et al. 2014

Mayo Clinic Proceedings

View full text Add to dashboard Cite

The prevalence of skin and soft tissue infections (SSTIs) has been increasing in the United States. These infections are associated with an increase in hospital admissions. Hospitalists play an increasingly important role in the management of these infections and need to use hospital resources efficiently and effectively. When available, observation units are useful for treating low-risk patients who do not require hospital admission. Imaging tools may help to exclude abscesses and necrotizing soft tissue infections; however, surgical exploration remains the principal means of diagnosing necrotizing soft tissue infections. The most common pathogens that cause SSTIs are streptococci and Staphylococcus aureus. Methicillin-resistant S aureus (MRSA) is a prevalent pathogen, and concerns are increasing regarding the unclear distinctions between community-acquired and hospital-acquired MRSA. Other less frequent pathogens that cause SSTIs include Enterococcus species, Escherichia coli, Klebsiella species, Enterobacter species, and Pseudomonas aeruginosa. Cephalexin and clindamycin are suitable options for infections caused by streptococcal species and methicillin-susceptible S aureus. The increasing resistance of S aureus and Streptococcus pyogenes to erythromycin limits its use in these infections, and better alternatives are available. Parenteral cefazolin, nafcillin, or oxacillin can be used in hospitalized patients with nonpurulent cellulitis caused by streptococci and methicillin-susceptible S aureus. When oral MRSA therapy is indicated, clindamycin, doxycycline, trimethoprim-sulfamethoxazole, or linezolid is appropriate. Vancomycin, linezolid, daptomycin, tigecycline, telavancin, and ceftaroline fosamil are intravenous options that should be used in MRSA infections that require patient hospitalization. In the treatment of patients with SSTIs, hospitalists are at the forefront of providing proper patient care that reduces hospital costs, duration of therapy, and therapeutic failures. This review updates guidelines on the management of SSTIs with a focus on infections caused by S aureus, particularly MRSA, and outlines the role of the hospitalist in the effective management of SSTIs.

show abstract

“…In order to evaluate the antimicrobial properties of the different parts of a mobile phone (screen, cover, felt), each one was individually coated by different sputtering conditions (Table 2), then the inhibition halo test was performed in accordance to National Committee for Clinical Laboratory Standards (NCCLS M2-A9 [40]) using a standard Staphylococcus aureus strain (ATCC 29213), which is a leading cause of infections [41]. The samples were placed in contact with an agar plate uniformly covered with a standard bacterial broth and incubated overnight at 35 • C; subsequently the inhibition halo was observed and measured.…”

Section: Antibacterial Testsmentioning

confidence: 99%

Silver nanocluster-silica composite antibacterial coatings for materials to be used in mobile telephones

Miola

Perero

Ferraris

et al. 2014

Applied Surface Science

View full text Add to dashboard Cite

a b s t r a c tAntibacterial coatings containing different amount of metallic silver nanoclusters embedded in a silica matrix have been deposited by co-sputtering technique on several different polymers used in mobile telephones components such as: screens, covers, and microphone felts.Sputtering parameters have been varied to obtain different coating thickness and silver content, in order to meet antibacterial, aesthetic and functional requirements for each component. In particular, an antibacterial functionality has been obtained for screens, covers and felts without affecting their respective transparency, aesthetic and acoustic properties.The optimal parameters for each part have been used to obtain an antibacterial mobile telephone suitable for personnel operating in hospitals or other environments with potentially high bacterial contamination.

show abstract

Microbiology of skin and soft tissue infections in the age of community-acquired methicillin-resistant Staphylococcus aureus

Cited by 84 publications

References 32 publications

Changing Susceptibility of Staphylococcus aureus in a US Pediatric Population

Changing Susceptibility of Staphylococcus aureus in a US Pediatric Population

Hospitalist Perspective on the Treatment of Skin and Soft Tissue Infections

Silver nanocluster-silica composite antibacterial coatings for materials to be used in mobile telephones

Contact Info

Product

Resources

About