Microbiology of Surgical Site Infections after Gastrointestinal Surgery in the South Region of The Netherlands

Abstract

The comparison between wound swabs taken in the first 48 h after a surgical procedure and swabs in the 30 days thereafter provides important information concerning the microbiology of SSIs and the development of antibiotic resistance of the causative agents over time.

Bacterial Epidemiology and Antimicrobial Resistance in the Surgery Wards of a Large Teaching Hospital in Southern Italy

“…This caused the re-emergence of the problem in the late 1990s and at the beginning of the new millennium, with a growing demand for multicenter studies that would contextualize the problem of either the epidemiology of these infections and the increasing antibiotic resistance or the increasingly innovative mechanisms put in place by pathogens to evade the action of antibiotics. 1 Currently, the main problems related to antibiotic resistance consist in the increasing prevalence of extended spectrum beta-lactamases (ESBLs) producing Enterobacteriaceae , and in the increasing intra-hospital presence of methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE), even though the spread of multi-drug resistant (MDR) bacteria greatly differs according to the geographic areas. 2 – 5 Knowledge of the local epidemiology of antibiotic resistance may help to develop therapeutic strategies and stewardship of more effective measures to optimize therapeutic outcomes and reduce the length of hospital stay.…”

Negative pressure wound therapy for surgical site infections: A systematic review and meta‐analysis

“…The guidelines (Allegranzi et al, 2016;Ban et al, 2017) (Ban et al, 2017;Darouiche et al, 2010;Moremi et al, 2018;Ramcharan et al, 2014). In recent years, prevalence of S. aureus and P. aeruginosa has increased.…”

“…Because studies spanned long periods, had differences in infection site, and data about the studies included was limited, we did not analyze pathogens, type of antibiotic used, or length of treatment. The guidelines (Allegranzi et al, 2016; Ban et al, 2017) established by WHO and Society of Surgical Infectious Diseases state that the common pathogens of healthcare‐associated/hospital‐acquired infections are Escherichia coli , Staphylococcus aureus , Klebsiella pneumoniae , Acinetobacter baumannii , Pseudomonas aeruginosa , Proteus mirabilis , Clostridium perfringens and Streptococcus (Ban et al, 2017; Darouiche et al, 2010; Moremi et al, 2018; Ramcharan et al, 2014). In recent years, prevalence of S. aureus and P. aeruginosa has increased.…”

Review of the Appropriateness of Surgical Antimicrobial Prophylaxis

“…Khan et al stated that only 9.5% of the surgeons adhered to guidelines concerning correct choice [33]. Ramcharan et al stated that cefuroxime or cefazolin is used commonly as a prophylactic agent and the rate of appropriateness is high [56]. Eisner et al reported that the most commonly used antibiotics for surgical prophylaxis were cephalosporins and in their study the most frequently used antibiotics were cefuroxime [57].…”