Microbiome at sites of gingival recession in children with Hutchinson–Gilford progeria syndrome

Abstract

Typical periodontal pathogens were not present at sites with gingival recession in HGPS children. The microbial compositions of sites of gingival recession and attachment loss in HGPS were generally more similar to those of periodontal health than periodontal disease. Species other than typical periodontal pathogens may be involved in this recession.

Oral Manifestations and Craniofacial Characteristics of Hutchinson-Gilford Progeria Syndrome: A Case Report

“…The literature suggests that individuals with HGPS have a high incidence of dental caries and gingivitis. [13][14][15][16][17]19 In the present case, gingivitis was associated with a greater presence of biofilm and lower toothbrushing frequency at home. It was possible to maintain oral health throughout the entire follow-up period through simple preventive measures.…”

“…The considerable variation in oral findings associated with HGPS described in the literature is likely due to the low prevalence of this syndrome. 10,13,16 Moreover, the increase in life expectancy of affected individuals leads to new clinical situations determined by the lifecycle itself. The most relevant oral manifestations can be considered the result of incompatibility determined by deficient jaw growth and the normal morphological/anatomical development of the teeth.…”